Terconazole, an Azole Antifungal Drug, Increases Cytotoxicity in Antimitotic Drug-Treated Resistant Cancer Cells with Substrate-Specific P-gp Inhibitory Activity

Azole antifungal drugs have been shown to enhance the cytotoxicity of antimitotic drugs in P-glycoprotein (P-gp)-overexpressing-resistant cancer cells. Herein, we examined two azole antifungal drugs, terconazole (TCZ) and butoconazole (BTZ), previously unexplored in resistant cancers. We found that...

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Detalles Bibliográficos
Autores principales: Lee, Ji Sun, Oh, Yunmoon, Park, Jae Hyeon, Kyung, So Young, Kim, Hyung Sik, Yoon, Sungpil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696874/
https://www.ncbi.nlm.nih.gov/pubmed/36430288
http://dx.doi.org/10.3390/ijms232213809

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