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Mitochondrial Alterations in Neurons Derived from the Murine App(NL-F) Knock-In Model of Alzheimer’s Disease
BACKGROUND: Alzheimer’s disease (AD) research has relied on mouse models overexpressing human mutant A βPP; however, newer generation knock-in models allow for physiological expression of amyloid-β protein precursor (AβPP) containing familial AD mutations where murine AβPP is edited with a humanized...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697055/ https://www.ncbi.nlm.nih.gov/pubmed/36155507 http://dx.doi.org/10.3233/JAD-220383 |