Cargando…

Epidemiological Survey of the Main Tick-Borne Pathogens Infecting Dogs from the Republic of Moldova

Despite the significant burden of tick-borne diseases (TBDs), epidemiologic studies are missing, and TBD awareness is low in the Republic of Moldova. Our study is the first to assess the prevalence of the main tick-borne pathogens (TBPs) infecting dogs in this country and associated risk factors. In...

Descripción completa

Detalles Bibliográficos
Autores principales: D’Amico, Gianluca, Ionică, Angela Monica, Györke, Adriana, Dumitrache, Mirabela Oana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697118/
https://www.ncbi.nlm.nih.gov/pubmed/36365018
http://dx.doi.org/10.3390/pathogens11111267
_version_ 1784838480992403456
author D’Amico, Gianluca
Ionică, Angela Monica
Györke, Adriana
Dumitrache, Mirabela Oana
author_facet D’Amico, Gianluca
Ionică, Angela Monica
Györke, Adriana
Dumitrache, Mirabela Oana
author_sort D’Amico, Gianluca
collection PubMed
description Despite the significant burden of tick-borne diseases (TBDs), epidemiologic studies are missing, and TBD awareness is low in the Republic of Moldova. Our study is the first to assess the prevalence of the main tick-borne pathogens (TBPs) infecting dogs in this country and associated risk factors. In this cross-sectional, multi-centre study (June 2018–July 2019), blood samples were collected from dogs presenting in veterinary clinics (Chişinău: N = 30) and hosted in public dog shelters (Cahul: N = 42; Chişinău: N = 48). TBPs were assessed by molecular techniques and risk factors by the logistic regression model. Hepatozoon canis was the most prevalent TBP (15.8% [19/120]), followed by Babesia canis (11.7% [14/120]), Anaplasma phagocytophilum (5.8% [7/120]), and Bartonella spp. (0.8% [1/120]). Blood samples tested negative for Borrelia spp., Rickettsia spp., Francisella tularensis, Anaplasma platys, and Ehrlichia canis. Dogs originating from the veterinary clinics had a higher prevalence of A. phagocytophilum infection than those from the shelters (16.6% versus 2.2%, respectively, p = 0.0292; OR: 27.0 [95%CI: 1.4–521.9]). Dogs from Chișinău had a higher prevalence of Hepatozoon canis infection versus those from Cahul (19.2% versus 9.5%, respectively, p = 0.0295; OR: 3.9 [95%CI: 1.1–13.4]). We recommend routine use of acaricides and deworming of dogs to prevent or/and limit TBD spread. Further TBD surveillance studies are needed.
format Online
Article
Text
id pubmed-9697118
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-96971182022-11-26 Epidemiological Survey of the Main Tick-Borne Pathogens Infecting Dogs from the Republic of Moldova D’Amico, Gianluca Ionică, Angela Monica Györke, Adriana Dumitrache, Mirabela Oana Pathogens Article Despite the significant burden of tick-borne diseases (TBDs), epidemiologic studies are missing, and TBD awareness is low in the Republic of Moldova. Our study is the first to assess the prevalence of the main tick-borne pathogens (TBPs) infecting dogs in this country and associated risk factors. In this cross-sectional, multi-centre study (June 2018–July 2019), blood samples were collected from dogs presenting in veterinary clinics (Chişinău: N = 30) and hosted in public dog shelters (Cahul: N = 42; Chişinău: N = 48). TBPs were assessed by molecular techniques and risk factors by the logistic regression model. Hepatozoon canis was the most prevalent TBP (15.8% [19/120]), followed by Babesia canis (11.7% [14/120]), Anaplasma phagocytophilum (5.8% [7/120]), and Bartonella spp. (0.8% [1/120]). Blood samples tested negative for Borrelia spp., Rickettsia spp., Francisella tularensis, Anaplasma platys, and Ehrlichia canis. Dogs originating from the veterinary clinics had a higher prevalence of A. phagocytophilum infection than those from the shelters (16.6% versus 2.2%, respectively, p = 0.0292; OR: 27.0 [95%CI: 1.4–521.9]). Dogs from Chișinău had a higher prevalence of Hepatozoon canis infection versus those from Cahul (19.2% versus 9.5%, respectively, p = 0.0295; OR: 3.9 [95%CI: 1.1–13.4]). We recommend routine use of acaricides and deworming of dogs to prevent or/and limit TBD spread. Further TBD surveillance studies are needed. MDPI 2022-10-30 /pmc/articles/PMC9697118/ /pubmed/36365018 http://dx.doi.org/10.3390/pathogens11111267 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
D’Amico, Gianluca
Ionică, Angela Monica
Györke, Adriana
Dumitrache, Mirabela Oana
Epidemiological Survey of the Main Tick-Borne Pathogens Infecting Dogs from the Republic of Moldova
title Epidemiological Survey of the Main Tick-Borne Pathogens Infecting Dogs from the Republic of Moldova
title_full Epidemiological Survey of the Main Tick-Borne Pathogens Infecting Dogs from the Republic of Moldova
title_fullStr Epidemiological Survey of the Main Tick-Borne Pathogens Infecting Dogs from the Republic of Moldova
title_full_unstemmed Epidemiological Survey of the Main Tick-Borne Pathogens Infecting Dogs from the Republic of Moldova
title_short Epidemiological Survey of the Main Tick-Borne Pathogens Infecting Dogs from the Republic of Moldova
title_sort epidemiological survey of the main tick-borne pathogens infecting dogs from the republic of moldova
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697118/
https://www.ncbi.nlm.nih.gov/pubmed/36365018
http://dx.doi.org/10.3390/pathogens11111267
work_keys_str_mv AT damicogianluca epidemiologicalsurveyofthemaintickbornepathogensinfectingdogsfromtherepublicofmoldova
AT ionicaangelamonica epidemiologicalsurveyofthemaintickbornepathogensinfectingdogsfromtherepublicofmoldova
AT gyorkeadriana epidemiologicalsurveyofthemaintickbornepathogensinfectingdogsfromtherepublicofmoldova
AT dumitrachemirabelaoana epidemiologicalsurveyofthemaintickbornepathogensinfectingdogsfromtherepublicofmoldova