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Epidemiological Survey of the Main Tick-Borne Pathogens Infecting Dogs from the Republic of Moldova
Despite the significant burden of tick-borne diseases (TBDs), epidemiologic studies are missing, and TBD awareness is low in the Republic of Moldova. Our study is the first to assess the prevalence of the main tick-borne pathogens (TBPs) infecting dogs in this country and associated risk factors. In...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697118/ https://www.ncbi.nlm.nih.gov/pubmed/36365018 http://dx.doi.org/10.3390/pathogens11111267 |
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author | D’Amico, Gianluca Ionică, Angela Monica Györke, Adriana Dumitrache, Mirabela Oana |
author_facet | D’Amico, Gianluca Ionică, Angela Monica Györke, Adriana Dumitrache, Mirabela Oana |
author_sort | D’Amico, Gianluca |
collection | PubMed |
description | Despite the significant burden of tick-borne diseases (TBDs), epidemiologic studies are missing, and TBD awareness is low in the Republic of Moldova. Our study is the first to assess the prevalence of the main tick-borne pathogens (TBPs) infecting dogs in this country and associated risk factors. In this cross-sectional, multi-centre study (June 2018–July 2019), blood samples were collected from dogs presenting in veterinary clinics (Chişinău: N = 30) and hosted in public dog shelters (Cahul: N = 42; Chişinău: N = 48). TBPs were assessed by molecular techniques and risk factors by the logistic regression model. Hepatozoon canis was the most prevalent TBP (15.8% [19/120]), followed by Babesia canis (11.7% [14/120]), Anaplasma phagocytophilum (5.8% [7/120]), and Bartonella spp. (0.8% [1/120]). Blood samples tested negative for Borrelia spp., Rickettsia spp., Francisella tularensis, Anaplasma platys, and Ehrlichia canis. Dogs originating from the veterinary clinics had a higher prevalence of A. phagocytophilum infection than those from the shelters (16.6% versus 2.2%, respectively, p = 0.0292; OR: 27.0 [95%CI: 1.4–521.9]). Dogs from Chișinău had a higher prevalence of Hepatozoon canis infection versus those from Cahul (19.2% versus 9.5%, respectively, p = 0.0295; OR: 3.9 [95%CI: 1.1–13.4]). We recommend routine use of acaricides and deworming of dogs to prevent or/and limit TBD spread. Further TBD surveillance studies are needed. |
format | Online Article Text |
id | pubmed-9697118 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96971182022-11-26 Epidemiological Survey of the Main Tick-Borne Pathogens Infecting Dogs from the Republic of Moldova D’Amico, Gianluca Ionică, Angela Monica Györke, Adriana Dumitrache, Mirabela Oana Pathogens Article Despite the significant burden of tick-borne diseases (TBDs), epidemiologic studies are missing, and TBD awareness is low in the Republic of Moldova. Our study is the first to assess the prevalence of the main tick-borne pathogens (TBPs) infecting dogs in this country and associated risk factors. In this cross-sectional, multi-centre study (June 2018–July 2019), blood samples were collected from dogs presenting in veterinary clinics (Chişinău: N = 30) and hosted in public dog shelters (Cahul: N = 42; Chişinău: N = 48). TBPs were assessed by molecular techniques and risk factors by the logistic regression model. Hepatozoon canis was the most prevalent TBP (15.8% [19/120]), followed by Babesia canis (11.7% [14/120]), Anaplasma phagocytophilum (5.8% [7/120]), and Bartonella spp. (0.8% [1/120]). Blood samples tested negative for Borrelia spp., Rickettsia spp., Francisella tularensis, Anaplasma platys, and Ehrlichia canis. Dogs originating from the veterinary clinics had a higher prevalence of A. phagocytophilum infection than those from the shelters (16.6% versus 2.2%, respectively, p = 0.0292; OR: 27.0 [95%CI: 1.4–521.9]). Dogs from Chișinău had a higher prevalence of Hepatozoon canis infection versus those from Cahul (19.2% versus 9.5%, respectively, p = 0.0295; OR: 3.9 [95%CI: 1.1–13.4]). We recommend routine use of acaricides and deworming of dogs to prevent or/and limit TBD spread. Further TBD surveillance studies are needed. MDPI 2022-10-30 /pmc/articles/PMC9697118/ /pubmed/36365018 http://dx.doi.org/10.3390/pathogens11111267 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article D’Amico, Gianluca Ionică, Angela Monica Györke, Adriana Dumitrache, Mirabela Oana Epidemiological Survey of the Main Tick-Borne Pathogens Infecting Dogs from the Republic of Moldova |
title | Epidemiological Survey of the Main Tick-Borne Pathogens Infecting Dogs from the Republic of Moldova |
title_full | Epidemiological Survey of the Main Tick-Borne Pathogens Infecting Dogs from the Republic of Moldova |
title_fullStr | Epidemiological Survey of the Main Tick-Borne Pathogens Infecting Dogs from the Republic of Moldova |
title_full_unstemmed | Epidemiological Survey of the Main Tick-Borne Pathogens Infecting Dogs from the Republic of Moldova |
title_short | Epidemiological Survey of the Main Tick-Borne Pathogens Infecting Dogs from the Republic of Moldova |
title_sort | epidemiological survey of the main tick-borne pathogens infecting dogs from the republic of moldova |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697118/ https://www.ncbi.nlm.nih.gov/pubmed/36365018 http://dx.doi.org/10.3390/pathogens11111267 |
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