Carvedilol Precipitation Inhibition by the Incorporation of Polymeric Precipitation Inhibitors Using a Stable Amorphous Solid Dispersion Approach: Formulation, Characterization, and In Vitro In Vivo Evaluation

An amorphous solid dispersion (ASD) of carvedilol (CVL) was prepared via the solvent evaporation method, using cellulose derivatives as polymeric precipitation inhibitors (PPIs). The prepared ASDs existed in the amorphous phase, as revealed by X-ray powder diffraction (XRPD) and scanning electron mi...

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Detalles Bibliográficos
Autores principales: Ravikumar, Akhila Akkihebbal, Kulkarni, Parthasarathi K., Osmani, Riyaz Ali M., Hani, Umme, Ghazwani, Mohammed, Fatease, Adel Al, Alamri, Ali H., Gowda, Devegowda V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697141/
https://www.ncbi.nlm.nih.gov/pubmed/36433104
http://dx.doi.org/10.3390/polym14224977

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