The Lack of STING Impairs the MHC-I Dependent Antigen Presentation and JAK/STAT Signaling in Murine Macrophages

STING is a transmembrane ER resident protein that was initially described as a regulator of innate immune response triggered by viral DNA and later found to be involved in a broader range of immune processes. Here, we assessed its role in the antigen presentation by generating a STING KO macrophage...

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Detalles Bibliográficos
Autores principales: Caiazza, Carmen, Brusco, Teresa, D’Alessio, Federica, D’Agostino, Massimo, Avagliano, Angelica, Arcucci, Alessandro, Ambrosino, Concetta, Fiume, Giuseppe, Mallardo, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697192/
https://www.ncbi.nlm.nih.gov/pubmed/36430709
http://dx.doi.org/10.3390/ijms232214232

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