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Mouse Pharmacokinetics and In Vitro Metabolism of SH-11037 and SH-11008, Synthetic Homoisoflavonoids for Retinal Neovascularization

Cremastranone is a member of the homoisoflavanone family with anti-angiogenic activity in the eyes. SH-11037, a potent and selective synthetic homoisoflavonoid derived from cremastranone, was studied here for pharmacokinetics and metabolism characterization with a special focus on esterase-mediated...

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Detalles Bibliográficos
Autores principales: Kim, Eun-yeong, Lee, Bit, Kwon, Sangil, Corson, Timothy W., Seo, Seung-Yong, Lee, Kiho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697349/
https://www.ncbi.nlm.nih.gov/pubmed/36365089
http://dx.doi.org/10.3390/pharmaceutics14112270

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