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Mouse Pharmacokinetics and In Vitro Metabolism of SH-11037 and SH-11008, Synthetic Homoisoflavonoids for Retinal Neovascularization
Cremastranone is a member of the homoisoflavanone family with anti-angiogenic activity in the eyes. SH-11037, a potent and selective synthetic homoisoflavonoid derived from cremastranone, was studied here for pharmacokinetics and metabolism characterization with a special focus on esterase-mediated...
Autores principales: | Kim, Eun-yeong, Lee, Bit, Kwon, Sangil, Corson, Timothy W., Seo, Seung-Yong, Lee, Kiho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697349/ https://www.ncbi.nlm.nih.gov/pubmed/36365089 http://dx.doi.org/10.3390/pharmaceutics14112270 |
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