Cargando…

Cytoprotective Properties of a New Nanocomplex of Selenium with Taxifolin in the Cells of the Cerebral Cortex Exposed to Ischemia/Reoxygenation

The neuroprotective effect of the natural antioxidant taxifolin (TAX) is well known for ischemic pathologies. However, the limitations of taxifolin application are described—poor solubility, low ability to penetrate the blood–brain barrier, and side effects from high doses for stroke therapy. We pro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Varlamova, Elena G., Khabatova, Venera V., Gudkov, Sergey V., Plotnikov, Egor Y., Turovsky, Egor A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697510/ https://www.ncbi.nlm.nih.gov/pubmed/36432668 http://dx.doi.org/10.3390/pharmaceutics14112477

Ejemplares similares

Ca(2+)-Dependent Effects of the Selenium-Sorafenib Nanocomplex on Glioblastoma Cells and Astrocytes of the Cerebral Cortex: Anticancer Agent and Cytoprotector
por: Varlamova, Elena G., et al.
Publicado: (2023)

Pilot Study of Cytoprotective Mechanisms of Selenium Nanorods (SeNrs) under Ischemia-like Conditions on Cortical Astrocytes
por: Varlamova, Elena G., et al.
Publicado: (2023)

Size-Dependent Cytoprotective Effects of Selenium Nanoparticles during Oxygen-Glucose Deprivation in Brain Cortical Cells
por: Varlamova, Elena G., et al.
Publicado: (2022)

The Mechanisms Underlying the Protective Action of Selenium Nanoparticles against Ischemia/Reoxygenation Are Mediated by the Activation of the Ca(2+) Signaling System of Astrocytes and Reactive Astrogliosis
por: Varlamova, Elena G., et al.
Publicado: (2021)

Mechanisms Underlying the Protective Effect of the Peroxiredoxin-6 Are Mediated via the Protection of Astrocytes during Ischemia/Reoxygenation
por: Turovsky, Egor A., et al.
Publicado: (2021)

The Protective Mechanism of Deuterated Linoleic Acid Involves the Activation of the Ca(2+) Signaling System of Astrocytes in Ischemia In Vitro
por: Turovsky, Egor A., et al.
Publicado: (2021)

Features of the cytoprotective effect of selenium nanoparticles on primary cortical neurons and astrocytes during oxygen–glucose deprivation and reoxygenation
por: Turovsky, E. A., et al.
Publicado: (2022)

Comparative Analysis of the Cytotoxic Effect of a Complex of Selenium Nanoparticles Doped with Sorafenib, “Naked” Selenium Nanoparticles, and Sorafenib on Human Hepatocyte Carcinoma HepG2 Cells
por: Varlamova, Elena G., et al.
Publicado: (2022)

Neuronal Calcium Sensor-1 Protects Cortical Neurons from Hyperexcitation and Ca(2+) Overload during Ischemia by Protecting the Population of GABAergic Neurons
por: Varlamova, Elena G., et al.
Publicado: (2022)

Cerium Oxide Nanoparticles Protect Cortical Astrocytes from Oxygen–Glucose Deprivation through Activation of the Ca(2+) Signaling System
por: Varlamova, Elena G., et al.
Publicado: (2023)

Therapeutic Potential and Main Methods of Obtaining Selenium Nanoparticles
por: Varlamova, Elena G., et al.
Publicado: (2021)

Modulation of the Functional State of Mouse Neutrophils by Selenium Nanoparticles In Vivo
por: Mal’tseva, Valentina N., et al.
Publicado: (2022)

Mechanisms of the Cytotoxic Effect of Selenium Nanoparticles in Different Human Cancer Cell Lines
por: Varlamova, Elena G., et al.
Publicado: (2021)

Mechanism of Ca(2+)-Dependent Pro-Apoptotic Action of Selenium Nanoparticles, Mediated by Activation of Cx43 Hemichannels
por: Turovsky, Egor A., et al.
Publicado: (2021)

A Comparative Analysis of Neuroprotective Properties of Taxifolin and Its Water-Soluble Form in Ischemia of Cerebral Cortical Cells of the Mouse
por: Varlamova, Elena G., et al.
Publicado: (2023)

A Review of the Antibacterial, Fungicidal and Antiviral Properties of Selenium Nanoparticles
por: Serov, Dmitry A., et al.
Publicado: (2023)

Selenium Nanoparticles Can Influence the Immune Response Due to Interactions with Antibodies and Modulation of the Physiological State of Granulocytes
por: Khabatova, Venera V., et al.
Publicado: (2022)

Immunomodulatory and Anti-Inflammatory Properties of Selenium-Containing Agents: Their Role in the Regulation of Defense Mechanisms against COVID-19
por: Mal’tseva, Valentina N., et al.
Publicado: (2022)

THE MAIN CYTOTOXIC EFFECTS OF METHYLSELENINIC ACID ON VARIOUS CANCER CELLS
por: Varlamova, Elena G., et al.
Publicado: (2021)

Activation of Cx43 Hemichannels Induces the Generation of Ca(2+) Oscillations in White Adipocytes and Stimulates Lipolysis
por: Turovsky, Egor A., et al.
Publicado: (2021)

The Role of Selenoproteins SELENOM and SELENOT in the Regulation of Apoptosis, ER Stress, and Calcium Homeostasis in the A-172 Human Glioblastoma Cell Line
por: Varlamova, Elena G., et al.
Publicado: (2022)

Deletion of the Neuronal Transcription Factor Satb1 Induced Disturbance of the Kinome and Mechanisms of Hypoxic Preconditioning
por: Turovsky, Egor A., et al.
Publicado: (2023)

Molecular Mechanisms of the Cytotoxic Effect of Recombinant Selenoprotein SELENOM on Human Glioblastoma Cells
por: Rogachev, Vladimir V., et al.
Publicado: (2023)

Role of Satb1 and Satb2 Transcription Factors in the Glutamate Receptors Expression and Ca(2+) Signaling in the Cortical Neurons In Vitro
por: Turovsky, Egor A., et al.
Publicado: (2021)

Assembling the Puzzle of Taxifolin Polymorphism
por: Terekhov, Roman P., et al.
Publicado: (2020)

Investigation of Aggregation and Disaggregation of Self-Assembling Nano-Sized Clusters Consisting of Individual Iron Oxide Nanoparticles upon Interaction with HEWL Protein Molecules
por: Sarimov, Ruslan M., et al.
Publicado: (2022)

Deregulation of Ca(2+)-Signaling Systems in White Adipocytes, Manifested as the Loss of Rhythmic Activity, Underlies the Development of Multiple Hormonal Resistance at Obesity and Type 2 Diabetes
por: Turovsky, Egor A., et al.
Publicado: (2021)

Loss of ischemic tolerance with age: can we protect an old kidney
por: Plotnikov, Egor
Publicado: (2021)

Loss of ischemic tolerance with age: can we protect an old kidney
por: Plotnikov, Egor
Publicado: (2021)

Renal Lesions and Nephrotoxicity: Contemporary Challenges and Future Directions
por: Plotnikov, Egor
Publicado: (2023)

Mesenchymal stromal cell-derived extracellular vesicles afford neuroprotection by modulating PI3K/AKT pathway and calcium oscillations
por: Turovsky, Egor A., et al.
Publicado: (2022)

Impaired CO(2) sensitivity of astrocytes in a mouse model of Rett syndrome
por: Turovsky, Egor, et al.
Publicado: (2015)

Protective Properties of Spheroidal Taxifolin Form in Streptozotocin-Induced Diabetic Rats
por: Taldaev, Amir, et al.
Publicado: (2023)

The Role of Selenium Nanoparticles in the Treatment of Liver Pathologies of Various Natures
por: Goltyaev, Michael V., et al.
Publicado: (2023)

Editorial: Mitochondria in Renal Health and Disease
por: Plotnikov, Egor, et al.
Publicado: (2021)

Editorial: Mitochondria in Renal Health and Disease, Volume II
por: Plotnikov, Egor, et al.
Publicado: (2022)

Taxifolin protects rat against myocardial ischemia/reperfusion injury by modulating the mitochondrial apoptosis pathway
por: Tang, Zhenqiu, et al.
Publicado: (2019)

Cytoprotective Effect of Ferritin H in Renal Ischemia Reperfusion Injury
por: Hatcher, Heather C., et al.
Publicado: (2015)

Effects of Taxifolin on Osteoclastogenesis in vitro and in vivo
por: Cai, Cong, et al.
Publicado: (2018)

An insight into novel therapeutic potentials of taxifolin
por: Liu, Yang, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_2pch1l8r9dis5m850tl4iuaqg9