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Development of In Vitro Evaluation System for Assessing Drug Dissolution Considering Physiological Environment in Nasal Cavity

Estimating the dissolution behavior of a solid in the nasal mucus is challenging for solid dosage forms designed for the nasal application as the solid dissolves into nasal mucus and permeates through the mucosa. In the current study, the dissolution behavior of powders in the artificial nasal fluid...

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Detalles Bibliográficos
Autores principales: Inoue, Daisuke, Yamashita, Ayari, To, Hideto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697526/
https://www.ncbi.nlm.nih.gov/pubmed/36365167
http://dx.doi.org/10.3390/pharmaceutics14112350