MET Signaling Pathways, Resistance Mechanisms, and Opportunities for Target Therapies

The MET gene, known as MET proto-oncogene receptor tyrosine kinase, was first identified to induce tumor cell migration, invasion, and proliferation/survival through canonical RAS-CDC42-PAK-Rho kinase, RAS-MAPK, PI3K-AKT-mTOR, and β-catenin signaling pathways, and its driver mutations, such as MET g...

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Detalles Bibliográficos
Autores principales: Rivas, Solange, Marín, Arnaldo, Samtani, Suraj, González-Feliú, Evelin, Armisén, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697723/
https://www.ncbi.nlm.nih.gov/pubmed/36430388
http://dx.doi.org/10.3390/ijms232213898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697723/
https://www.ncbi.nlm.nih.gov/pubmed/36430388
http://dx.doi.org/10.3390/ijms232213898

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