Ligand Growing Experiments Suggested 4-amino and 4-ureido pyridazin-3(2H)-one as Novel Scaffold for FABP4 Inhibition

Fatty acid binding protein (FABP4) inhibitors are of synthetic and therapeutic interest and ongoing clinical studies indicate that they may be a promise for the treatment of cancer, as well as other diseases. As part of a broader research effort to develop more effective FABP4 inhibitors, we sought...

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Detalles Bibliográficos
Autores principales: Crocetti, Letizia, Floresta, Giuseppe, Zagni, Chiara, Merugu, Divya, Mazzacuva, Francesca, de Oliveira Silva, Renan Rodrigues, Vergelli, Claudia, Giovannoni, Maria Paola, Cilibrizzi, Agostino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697826/
https://www.ncbi.nlm.nih.gov/pubmed/36355506
http://dx.doi.org/10.3390/ph15111335

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