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Recombinant Expression in Pichia pastoris System of Three Potent Kv1.3 Channel Blockers: Vm24, Anuroctoxin, and Ts6

The Kv1.3 channel has become a therapeutic target for the treatment of various diseases. Several Kv1.3 channel blockers have been characterized from scorpion venom; however, extensive studies require amounts of toxin that cannot be readily obtained directly from venoms. The Pichia pastoris expressio...

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Detalles Bibliográficos
Autores principales: Borrego, Jesús, Naseem, Muhammad Umair, Sehgal, Al Nasar Ahmed, Panda, Lipsa Rani, Shakeel, Kashmala, Gaspar, Attila, Nagy, Cynthia, Varga, Zoltan, Panyi, Gyorgy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697831/
https://www.ncbi.nlm.nih.gov/pubmed/36422036
http://dx.doi.org/10.3390/jof8111215