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Ileocolonic-Targeted JAK Inhibitor: A Safer and More Effective Treatment for Inflammatory Bowel Disease
Janus kinase (JAK) inhibitors, such as tofacitinib (Xeljanz) and filgotinib (Jyseleca), have been approved for treatment of ulcerative colitis with several other JAK inhibitors in late-stage clinical trials for inflammatory bowel disease (IBD). Despite their impressive efficacy, the risk of adverse...
Autores principales: | Yadav, Vipul, House, Aileen, Matiz, Silvia, McCoubrey, Laura E., Bettano, Kimberly A., Bhave, Leena, Wang, Meiyao, Fan, Peter, Zhou, Siqun, Woodhouse, Janice D., Poimenidou, Eirini, Dou, Liu, Basit, Abdul W., Moy, Lily Y., Saklatvala, Robert, Hegde, Laxminarayan G., Yu, Hongshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698010/ https://www.ncbi.nlm.nih.gov/pubmed/36365202 http://dx.doi.org/10.3390/pharmaceutics14112385 |
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