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Prevalence of Venous Thromboembolism in Intensive Care Units: A Meta-Analysis
Objective: Venous thromboembolism (VTE) is a life threating complication in intensive care units (ICUs). This study aimed to pool the prevalence of VTE and examined the risk factors of VTE in intensive care patients worldwide. Methods: A systematic search in PubMed, EMBASE and Web of Science databas...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698016/ https://www.ncbi.nlm.nih.gov/pubmed/36431168 http://dx.doi.org/10.3390/jcm11226691 |
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author | Gao, Xiaoyu Zeng, Liangnan Wang, Haorun Zeng, Shan Tian, Junjie Chen, Ligang Peng, Tangming |
author_facet | Gao, Xiaoyu Zeng, Liangnan Wang, Haorun Zeng, Shan Tian, Junjie Chen, Ligang Peng, Tangming |
author_sort | Gao, Xiaoyu |
collection | PubMed |
description | Objective: Venous thromboembolism (VTE) is a life threating complication in intensive care units (ICUs). This study aimed to pool the prevalence of VTE and examined the risk factors of VTE in intensive care patients worldwide. Methods: A systematic search in PubMed, EMBASE and Web of Science databases was performed. Studies reported that the data on the prevalence of VTE or relevant information were synthesized using a random-effects model. Results: A total of 42 studies reporting on 27,344 patients were included. The pooled prevalence of VTE was 10.0% (95% CI: 7.0–14.0%). Subgroup and metaregression analyses found that thromboprophylaxis strategy, simplified acute physiology score (SAPS II), age, study quality, sample size, malignancy, sex, spinal cord injury and injury severity score (ISS) moderated the prevalence of VTE in intensive care patients. Conclusions: The present meta-analysis revealed a high prevalence of VTE in critically ill patients. The risk factors of VTE included thromboprophylaxis strategy, SAPS II, age, malignancy, sex, spinal cord injury and ISS. Therefore, we need to pay more attention to high-risk populations of VTE in intensive care patients. |
format | Online Article Text |
id | pubmed-9698016 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96980162022-11-26 Prevalence of Venous Thromboembolism in Intensive Care Units: A Meta-Analysis Gao, Xiaoyu Zeng, Liangnan Wang, Haorun Zeng, Shan Tian, Junjie Chen, Ligang Peng, Tangming J Clin Med Review Objective: Venous thromboembolism (VTE) is a life threating complication in intensive care units (ICUs). This study aimed to pool the prevalence of VTE and examined the risk factors of VTE in intensive care patients worldwide. Methods: A systematic search in PubMed, EMBASE and Web of Science databases was performed. Studies reported that the data on the prevalence of VTE or relevant information were synthesized using a random-effects model. Results: A total of 42 studies reporting on 27,344 patients were included. The pooled prevalence of VTE was 10.0% (95% CI: 7.0–14.0%). Subgroup and metaregression analyses found that thromboprophylaxis strategy, simplified acute physiology score (SAPS II), age, study quality, sample size, malignancy, sex, spinal cord injury and injury severity score (ISS) moderated the prevalence of VTE in intensive care patients. Conclusions: The present meta-analysis revealed a high prevalence of VTE in critically ill patients. The risk factors of VTE included thromboprophylaxis strategy, SAPS II, age, malignancy, sex, spinal cord injury and ISS. Therefore, we need to pay more attention to high-risk populations of VTE in intensive care patients. MDPI 2022-11-11 /pmc/articles/PMC9698016/ /pubmed/36431168 http://dx.doi.org/10.3390/jcm11226691 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Gao, Xiaoyu Zeng, Liangnan Wang, Haorun Zeng, Shan Tian, Junjie Chen, Ligang Peng, Tangming Prevalence of Venous Thromboembolism in Intensive Care Units: A Meta-Analysis |
title | Prevalence of Venous Thromboembolism in Intensive Care Units: A Meta-Analysis |
title_full | Prevalence of Venous Thromboembolism in Intensive Care Units: A Meta-Analysis |
title_fullStr | Prevalence of Venous Thromboembolism in Intensive Care Units: A Meta-Analysis |
title_full_unstemmed | Prevalence of Venous Thromboembolism in Intensive Care Units: A Meta-Analysis |
title_short | Prevalence of Venous Thromboembolism in Intensive Care Units: A Meta-Analysis |
title_sort | prevalence of venous thromboembolism in intensive care units: a meta-analysis |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698016/ https://www.ncbi.nlm.nih.gov/pubmed/36431168 http://dx.doi.org/10.3390/jcm11226691 |
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