Cargando…

Prevalence of Venous Thromboembolism in Intensive Care Units: A Meta-Analysis

Objective: Venous thromboembolism (VTE) is a life threating complication in intensive care units (ICUs). This study aimed to pool the prevalence of VTE and examined the risk factors of VTE in intensive care patients worldwide. Methods: A systematic search in PubMed, EMBASE and Web of Science databas...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Xiaoyu, Zeng, Liangnan, Wang, Haorun, Zeng, Shan, Tian, Junjie, Chen, Ligang, Peng, Tangming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698016/
https://www.ncbi.nlm.nih.gov/pubmed/36431168
http://dx.doi.org/10.3390/jcm11226691
_version_ 1784838710889545728
author Gao, Xiaoyu
Zeng, Liangnan
Wang, Haorun
Zeng, Shan
Tian, Junjie
Chen, Ligang
Peng, Tangming
author_facet Gao, Xiaoyu
Zeng, Liangnan
Wang, Haorun
Zeng, Shan
Tian, Junjie
Chen, Ligang
Peng, Tangming
author_sort Gao, Xiaoyu
collection PubMed
description Objective: Venous thromboembolism (VTE) is a life threating complication in intensive care units (ICUs). This study aimed to pool the prevalence of VTE and examined the risk factors of VTE in intensive care patients worldwide. Methods: A systematic search in PubMed, EMBASE and Web of Science databases was performed. Studies reported that the data on the prevalence of VTE or relevant information were synthesized using a random-effects model. Results: A total of 42 studies reporting on 27,344 patients were included. The pooled prevalence of VTE was 10.0% (95% CI: 7.0–14.0%). Subgroup and metaregression analyses found that thromboprophylaxis strategy, simplified acute physiology score (SAPS II), age, study quality, sample size, malignancy, sex, spinal cord injury and injury severity score (ISS) moderated the prevalence of VTE in intensive care patients. Conclusions: The present meta-analysis revealed a high prevalence of VTE in critically ill patients. The risk factors of VTE included thromboprophylaxis strategy, SAPS II, age, malignancy, sex, spinal cord injury and ISS. Therefore, we need to pay more attention to high-risk populations of VTE in intensive care patients.
format Online
Article
Text
id pubmed-9698016
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-96980162022-11-26 Prevalence of Venous Thromboembolism in Intensive Care Units: A Meta-Analysis Gao, Xiaoyu Zeng, Liangnan Wang, Haorun Zeng, Shan Tian, Junjie Chen, Ligang Peng, Tangming J Clin Med Review Objective: Venous thromboembolism (VTE) is a life threating complication in intensive care units (ICUs). This study aimed to pool the prevalence of VTE and examined the risk factors of VTE in intensive care patients worldwide. Methods: A systematic search in PubMed, EMBASE and Web of Science databases was performed. Studies reported that the data on the prevalence of VTE or relevant information were synthesized using a random-effects model. Results: A total of 42 studies reporting on 27,344 patients were included. The pooled prevalence of VTE was 10.0% (95% CI: 7.0–14.0%). Subgroup and metaregression analyses found that thromboprophylaxis strategy, simplified acute physiology score (SAPS II), age, study quality, sample size, malignancy, sex, spinal cord injury and injury severity score (ISS) moderated the prevalence of VTE in intensive care patients. Conclusions: The present meta-analysis revealed a high prevalence of VTE in critically ill patients. The risk factors of VTE included thromboprophylaxis strategy, SAPS II, age, malignancy, sex, spinal cord injury and ISS. Therefore, we need to pay more attention to high-risk populations of VTE in intensive care patients. MDPI 2022-11-11 /pmc/articles/PMC9698016/ /pubmed/36431168 http://dx.doi.org/10.3390/jcm11226691 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Gao, Xiaoyu
Zeng, Liangnan
Wang, Haorun
Zeng, Shan
Tian, Junjie
Chen, Ligang
Peng, Tangming
Prevalence of Venous Thromboembolism in Intensive Care Units: A Meta-Analysis
title Prevalence of Venous Thromboembolism in Intensive Care Units: A Meta-Analysis
title_full Prevalence of Venous Thromboembolism in Intensive Care Units: A Meta-Analysis
title_fullStr Prevalence of Venous Thromboembolism in Intensive Care Units: A Meta-Analysis
title_full_unstemmed Prevalence of Venous Thromboembolism in Intensive Care Units: A Meta-Analysis
title_short Prevalence of Venous Thromboembolism in Intensive Care Units: A Meta-Analysis
title_sort prevalence of venous thromboembolism in intensive care units: a meta-analysis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698016/
https://www.ncbi.nlm.nih.gov/pubmed/36431168
http://dx.doi.org/10.3390/jcm11226691
work_keys_str_mv AT gaoxiaoyu prevalenceofvenousthromboembolisminintensivecareunitsametaanalysis
AT zengliangnan prevalenceofvenousthromboembolisminintensivecareunitsametaanalysis
AT wanghaorun prevalenceofvenousthromboembolisminintensivecareunitsametaanalysis
AT zengshan prevalenceofvenousthromboembolisminintensivecareunitsametaanalysis
AT tianjunjie prevalenceofvenousthromboembolisminintensivecareunitsametaanalysis
AT chenligang prevalenceofvenousthromboembolisminintensivecareunitsametaanalysis
AT pengtangming prevalenceofvenousthromboembolisminintensivecareunitsametaanalysis