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Sequence–Activity Relationship of ATCUN Peptides in the Context of Alzheimer’s Disease
Amino-terminal Cu(II) and Ni(II) (ATCUN) binding sequences are widespread in the biological world. Here, we report on the study of eight ATCUN peptides aimed at targeting copper ions and stopping the associated formation of reactive oxygen species (ROS). This study was actually more focused on Cu(Aβ...
Autores principales: | Lefèvre, Margot, Malikidogo, Kyangwi P., Esmieu, Charlène, Hureau, Christelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698028/ https://www.ncbi.nlm.nih.gov/pubmed/36432004 http://dx.doi.org/10.3390/molecules27227903 |
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