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Structural Optimization of Platinum Drugs to Improve the Drug-Loading and Antitumor Efficacy of PLGA Nanoparticles

Currently, molecular dynamics simulation is being widely applied to predict drug–polymer interaction, and to optimize drug delivery systems. Our study describes a combination of in silico and in vitro approaches aimed at improvement in polymer-based nanoparticle design for cancer treatment. We appli...

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Detalles Bibliográficos
Autores principales:	Sokol, Maria B., Chirkina, Margarita V., Yabbarov, Nikita G., Mollaeva, Mariia R., Podrugina, Tatyana A., Pavlova, Anna S., Temnov, Viktor V., Hathout, Rania M., Metwally, Abdelkader A., Nikolskaya, Elena D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698263/ https://www.ncbi.nlm.nih.gov/pubmed/36365151 http://dx.doi.org/10.3390/pharmaceutics14112333

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