Role of 5-HT2A, 5-HT2C, 5-HT1A and TAAR1 Receptors in the Head Twitch Response Induced by 5-Hydroxytryptophan and Psilocybin: Translational Implications

There is increasing interest in the therapeutic potential of psilocybin. In rodents, the serotonin precursor, 5-hydroxytryptophan (5-HTP) and psilocybin induce a characteristic 5-HT2A receptor (5-HT2AR)-mediated head twitch response (HTR), which is correlated with the human psychedelic trip. We exam...

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Detalles Bibliográficos
Autores principales: Shahar, Orr, Botvinnik, Alexander, Esh-Zuntz, Noam, Brownstien, Michal, Wolf, Rachel, Lotan, Amit, Wolf, Gilly, Lerer, Bernard, Lifschytz, Tzuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698447/
https://www.ncbi.nlm.nih.gov/pubmed/36430623
http://dx.doi.org/10.3390/ijms232214148

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