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Metal-Oxide FET Biosensor for Point-of-Care Testing: Overview and Perspective
Metal-oxide semiconducting materials are promising for building high-performance field-effect transistor (FET) based biochemical sensors. The existence of well-established top-down scalable manufacturing processes enables the reliable production of cost-effective yet high-performance sensors, two ke...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698540/ https://www.ncbi.nlm.nih.gov/pubmed/36432052 http://dx.doi.org/10.3390/molecules27227952 |
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author | Amen, Mohamed Taha Pham, Thuy Thi Thanh Cheah, Edward Tran, Duy Phu Thierry, Benjamin |
author_facet | Amen, Mohamed Taha Pham, Thuy Thi Thanh Cheah, Edward Tran, Duy Phu Thierry, Benjamin |
author_sort | Amen, Mohamed Taha |
collection | PubMed |
description | Metal-oxide semiconducting materials are promising for building high-performance field-effect transistor (FET) based biochemical sensors. The existence of well-established top-down scalable manufacturing processes enables the reliable production of cost-effective yet high-performance sensors, two key considerations toward the translation of such devices in real-life applications. Metal-oxide semiconductor FET biochemical sensors are especially well-suited to the development of Point-of-Care testing (PoCT) devices, as illustrated by the rapidly growing body of reports in the field. Yet, metal-oxide semiconductor FET sensors remain confined to date, mainly in academia. Toward accelerating the real-life translation of this exciting technology, we review the current literature and discuss the critical features underpinning the successful development of metal-oxide semiconductor FET-based PoCT devices that meet the stringent performance, manufacturing, and regulatory requirements of PoCT. |
format | Online Article Text |
id | pubmed-9698540 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96985402022-11-26 Metal-Oxide FET Biosensor for Point-of-Care Testing: Overview and Perspective Amen, Mohamed Taha Pham, Thuy Thi Thanh Cheah, Edward Tran, Duy Phu Thierry, Benjamin Molecules Review Metal-oxide semiconducting materials are promising for building high-performance field-effect transistor (FET) based biochemical sensors. The existence of well-established top-down scalable manufacturing processes enables the reliable production of cost-effective yet high-performance sensors, two key considerations toward the translation of such devices in real-life applications. Metal-oxide semiconductor FET biochemical sensors are especially well-suited to the development of Point-of-Care testing (PoCT) devices, as illustrated by the rapidly growing body of reports in the field. Yet, metal-oxide semiconductor FET sensors remain confined to date, mainly in academia. Toward accelerating the real-life translation of this exciting technology, we review the current literature and discuss the critical features underpinning the successful development of metal-oxide semiconductor FET-based PoCT devices that meet the stringent performance, manufacturing, and regulatory requirements of PoCT. MDPI 2022-11-17 /pmc/articles/PMC9698540/ /pubmed/36432052 http://dx.doi.org/10.3390/molecules27227952 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Amen, Mohamed Taha Pham, Thuy Thi Thanh Cheah, Edward Tran, Duy Phu Thierry, Benjamin Metal-Oxide FET Biosensor for Point-of-Care Testing: Overview and Perspective |
title | Metal-Oxide FET Biosensor for Point-of-Care Testing: Overview and Perspective |
title_full | Metal-Oxide FET Biosensor for Point-of-Care Testing: Overview and Perspective |
title_fullStr | Metal-Oxide FET Biosensor for Point-of-Care Testing: Overview and Perspective |
title_full_unstemmed | Metal-Oxide FET Biosensor for Point-of-Care Testing: Overview and Perspective |
title_short | Metal-Oxide FET Biosensor for Point-of-Care Testing: Overview and Perspective |
title_sort | metal-oxide fet biosensor for point-of-care testing: overview and perspective |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698540/ https://www.ncbi.nlm.nih.gov/pubmed/36432052 http://dx.doi.org/10.3390/molecules27227952 |
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