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Metal-Oxide FET Biosensor for Point-of-Care Testing: Overview and Perspective

Metal-oxide semiconducting materials are promising for building high-performance field-effect transistor (FET) based biochemical sensors. The existence of well-established top-down scalable manufacturing processes enables the reliable production of cost-effective yet high-performance sensors, two ke...

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Detalles Bibliográficos
Autores principales: Amen, Mohamed Taha, Pham, Thuy Thi Thanh, Cheah, Edward, Tran, Duy Phu, Thierry, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698540/
https://www.ncbi.nlm.nih.gov/pubmed/36432052
http://dx.doi.org/10.3390/molecules27227952
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author Amen, Mohamed Taha
Pham, Thuy Thi Thanh
Cheah, Edward
Tran, Duy Phu
Thierry, Benjamin
author_facet Amen, Mohamed Taha
Pham, Thuy Thi Thanh
Cheah, Edward
Tran, Duy Phu
Thierry, Benjamin
author_sort Amen, Mohamed Taha
collection PubMed
description Metal-oxide semiconducting materials are promising for building high-performance field-effect transistor (FET) based biochemical sensors. The existence of well-established top-down scalable manufacturing processes enables the reliable production of cost-effective yet high-performance sensors, two key considerations toward the translation of such devices in real-life applications. Metal-oxide semiconductor FET biochemical sensors are especially well-suited to the development of Point-of-Care testing (PoCT) devices, as illustrated by the rapidly growing body of reports in the field. Yet, metal-oxide semiconductor FET sensors remain confined to date, mainly in academia. Toward accelerating the real-life translation of this exciting technology, we review the current literature and discuss the critical features underpinning the successful development of metal-oxide semiconductor FET-based PoCT devices that meet the stringent performance, manufacturing, and regulatory requirements of PoCT.
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spelling pubmed-96985402022-11-26 Metal-Oxide FET Biosensor for Point-of-Care Testing: Overview and Perspective Amen, Mohamed Taha Pham, Thuy Thi Thanh Cheah, Edward Tran, Duy Phu Thierry, Benjamin Molecules Review Metal-oxide semiconducting materials are promising for building high-performance field-effect transistor (FET) based biochemical sensors. The existence of well-established top-down scalable manufacturing processes enables the reliable production of cost-effective yet high-performance sensors, two key considerations toward the translation of such devices in real-life applications. Metal-oxide semiconductor FET biochemical sensors are especially well-suited to the development of Point-of-Care testing (PoCT) devices, as illustrated by the rapidly growing body of reports in the field. Yet, metal-oxide semiconductor FET sensors remain confined to date, mainly in academia. Toward accelerating the real-life translation of this exciting technology, we review the current literature and discuss the critical features underpinning the successful development of metal-oxide semiconductor FET-based PoCT devices that meet the stringent performance, manufacturing, and regulatory requirements of PoCT. MDPI 2022-11-17 /pmc/articles/PMC9698540/ /pubmed/36432052 http://dx.doi.org/10.3390/molecules27227952 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Amen, Mohamed Taha
Pham, Thuy Thi Thanh
Cheah, Edward
Tran, Duy Phu
Thierry, Benjamin
Metal-Oxide FET Biosensor for Point-of-Care Testing: Overview and Perspective
title Metal-Oxide FET Biosensor for Point-of-Care Testing: Overview and Perspective
title_full Metal-Oxide FET Biosensor for Point-of-Care Testing: Overview and Perspective
title_fullStr Metal-Oxide FET Biosensor for Point-of-Care Testing: Overview and Perspective
title_full_unstemmed Metal-Oxide FET Biosensor for Point-of-Care Testing: Overview and Perspective
title_short Metal-Oxide FET Biosensor for Point-of-Care Testing: Overview and Perspective
title_sort metal-oxide fet biosensor for point-of-care testing: overview and perspective
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698540/
https://www.ncbi.nlm.nih.gov/pubmed/36432052
http://dx.doi.org/10.3390/molecules27227952
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