Dual Functionalized Liposomes for Selective Delivery of Poorly Soluble Drugs to Inflamed Brain Regions

Dual functionalized liposomes were developed to cross the blood–brain barrier (BBB) and to release their cargo in a pathological matrix metalloproteinase (MMP)-rich microenvironment. Liposomes were surface-functionalized with a modified peptide deriving from the receptor-binding domain of apolipopro...

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Detalles Bibliográficos
Autores principales: Giofrè, Sabrina, Renda, Antonio, Sesana, Silvia, Formicola, Beatrice, Vergani, Barbara, Leone, Biagio Eugenio, Denti, Vanna, Paglia, Giuseppe, Groppuso, Serena, Romeo, Valentina, Muzio, Luca, Balboni, Andrea, Menegon, Andrea, Antoniou, Antonia, Amenta, Arianna, Passarella, Daniele, Seneci, Pierfausto, Pellegrino, Sara, Re, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698607/
https://www.ncbi.nlm.nih.gov/pubmed/36365220
http://dx.doi.org/10.3390/pharmaceutics14112402

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