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A Physiologically Based Pharmacokinetic (PBPK) Modeling Framework for Mixtures of Dioxin-like Compounds

Humans are exposed to persistent organic pollutants, such as dioxin-like compounds (DLCs), as mixtures. Understanding and predicting the toxicokinetics and thus internal burden of major constituents of a DLC mixture is important for assessing their contributions to health risks. PBPK models, includi...

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Detalles Bibliográficos
Autores principales: Liu, Rongrui, Zacharewski, Tim R., Conolly, Rory B., Zhang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698634/
https://www.ncbi.nlm.nih.gov/pubmed/36422908
http://dx.doi.org/10.3390/toxics10110700