Cyclin-Dependent Kinase 5 Regulates cPLA2 Activity and Neuroinflammation in Parkinson’s Disease

Hyperactivation of cyclin-dependent kinase 5 (Cdk5) by p25, contributes to neuroinflammation causing neurodegeneration in Parkinson’s disease (PD) and Alzheimer’s disease. However, the mechanism by which Cdk5 induces neuroinflammation in the PD brain is largely unexplored. Here, we show that Cdk5 ph...

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Detalles Bibliográficos
Autores principales: Paul, Sangita, Fatihi, Saman, Sharma, Srishti, Kutum, Rintu, Fields, Raymond, Pant, Harish C., Thukral, Lipi, BK, Binukumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2022
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698719/
https://www.ncbi.nlm.nih.gov/pubmed/36351818
http://dx.doi.org/10.1523/ENEURO.0180-22.2022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698719/
https://www.ncbi.nlm.nih.gov/pubmed/36351818
http://dx.doi.org/10.1523/ENEURO.0180-22.2022

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