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Ultra-Fast Middle-Up Reversed Phase Liquid Chromatography Analysis of Complex Bispecific Antibodies Obtained in Less Than One Minute

This work illustrates the benefits and limitations of using ultra-short reversed phase liquid chromatography (RPLC) columns for the characterization of various complex bispecific antibodies after prolonged thermal stress at the middle-up level of analysis. First, we have demonstrated that alternativ...

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Detalles Bibliográficos
Autores principales:	Murisier, Amarande, D’Atri, Valentina, Pirner, Sebastian, Larraillet, Vincent, Fekete, Szabolcs, Lauber, Matthew, Guillarme, Davy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698801/ https://www.ncbi.nlm.nih.gov/pubmed/36365134 http://dx.doi.org/10.3390/pharmaceutics14112315

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