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A New Comestible Formulation of Parasiticide Fungi to Reduce the Risk of Soil-Transmitted Helminth Infections in a Canine Shelter

Dogs cared for in a shelter are dewormed every three–four months, but they all become infected one–two months later by the soil-transmitted helminths (STHs) Toxocara canis, Toxascaris leonina, Trichuris vulpis, and Ancylostoma caninum. For the purpose of reducing their risk of infection by decreasin...

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Autores principales: Viña, Cándido, Salmo, Rami, Pena, María Vilá, Palomero, Antonio Miguel, Hernández, José Ángel, Cazapal-Monteiro, Cristiana, Arias, María Sol, Sánchez-Andrade, Rita, Paz-Silva, Adolfo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698839/
https://www.ncbi.nlm.nih.gov/pubmed/36422641
http://dx.doi.org/10.3390/pathogens11111391
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author Viña, Cándido
Salmo, Rami
Pena, María Vilá
Palomero, Antonio Miguel
Hernández, José Ángel
Cazapal-Monteiro, Cristiana
Arias, María Sol
Sánchez-Andrade, Rita
Paz-Silva, Adolfo
author_facet Viña, Cándido
Salmo, Rami
Pena, María Vilá
Palomero, Antonio Miguel
Hernández, José Ángel
Cazapal-Monteiro, Cristiana
Arias, María Sol
Sánchez-Andrade, Rita
Paz-Silva, Adolfo
author_sort Viña, Cándido
collection PubMed
description Dogs cared for in a shelter are dewormed every three–four months, but they all become infected one–two months later by the soil-transmitted helminths (STHs) Toxocara canis, Toxascaris leonina, Trichuris vulpis, and Ancylostoma caninum. For the purpose of reducing their risk of infection by decreasing the survival of helminths’ infective stages in soil, chlamydospores of two parasiticide fungi, Mucor circinelloides (ovicide) and Duddingtonia flagrans (larvicide) were formulated as handmade edible gelatins and given three days per week for 17 months to 18 dogs (DRF, dogs receiving fungi); a second group was maintained without fungi (CD, control dogs). All individuals were dewormed at months 0, 3, 7, 10 and 13, and it was observed that the levels of helminths egg-output were reduced by 96–98% fourteen days after each treatment. Fecal egg counts of STHs were similar in both groups until the 6th–8th months, and then remained significantly lower in DRF than in CD (42–100% ascarids; 30–100% trichurids and ancylostomatids). According to the results, and considering that gelatin treats have always been fully accepted, it is concluded that this new formulation offers an efficient solution to decrease the risk of infection among dogs maintained in shelters, and is therefore recommended.
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spelling pubmed-96988392022-11-26 A New Comestible Formulation of Parasiticide Fungi to Reduce the Risk of Soil-Transmitted Helminth Infections in a Canine Shelter Viña, Cándido Salmo, Rami Pena, María Vilá Palomero, Antonio Miguel Hernández, José Ángel Cazapal-Monteiro, Cristiana Arias, María Sol Sánchez-Andrade, Rita Paz-Silva, Adolfo Pathogens Article Dogs cared for in a shelter are dewormed every three–four months, but they all become infected one–two months later by the soil-transmitted helminths (STHs) Toxocara canis, Toxascaris leonina, Trichuris vulpis, and Ancylostoma caninum. For the purpose of reducing their risk of infection by decreasing the survival of helminths’ infective stages in soil, chlamydospores of two parasiticide fungi, Mucor circinelloides (ovicide) and Duddingtonia flagrans (larvicide) were formulated as handmade edible gelatins and given three days per week for 17 months to 18 dogs (DRF, dogs receiving fungi); a second group was maintained without fungi (CD, control dogs). All individuals were dewormed at months 0, 3, 7, 10 and 13, and it was observed that the levels of helminths egg-output were reduced by 96–98% fourteen days after each treatment. Fecal egg counts of STHs were similar in both groups until the 6th–8th months, and then remained significantly lower in DRF than in CD (42–100% ascarids; 30–100% trichurids and ancylostomatids). According to the results, and considering that gelatin treats have always been fully accepted, it is concluded that this new formulation offers an efficient solution to decrease the risk of infection among dogs maintained in shelters, and is therefore recommended. MDPI 2022-11-21 /pmc/articles/PMC9698839/ /pubmed/36422641 http://dx.doi.org/10.3390/pathogens11111391 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Viña, Cándido
Salmo, Rami
Pena, María Vilá
Palomero, Antonio Miguel
Hernández, José Ángel
Cazapal-Monteiro, Cristiana
Arias, María Sol
Sánchez-Andrade, Rita
Paz-Silva, Adolfo
A New Comestible Formulation of Parasiticide Fungi to Reduce the Risk of Soil-Transmitted Helminth Infections in a Canine Shelter
title A New Comestible Formulation of Parasiticide Fungi to Reduce the Risk of Soil-Transmitted Helminth Infections in a Canine Shelter
title_full A New Comestible Formulation of Parasiticide Fungi to Reduce the Risk of Soil-Transmitted Helminth Infections in a Canine Shelter
title_fullStr A New Comestible Formulation of Parasiticide Fungi to Reduce the Risk of Soil-Transmitted Helminth Infections in a Canine Shelter
title_full_unstemmed A New Comestible Formulation of Parasiticide Fungi to Reduce the Risk of Soil-Transmitted Helminth Infections in a Canine Shelter
title_short A New Comestible Formulation of Parasiticide Fungi to Reduce the Risk of Soil-Transmitted Helminth Infections in a Canine Shelter
title_sort new comestible formulation of parasiticide fungi to reduce the risk of soil-transmitted helminth infections in a canine shelter
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698839/
https://www.ncbi.nlm.nih.gov/pubmed/36422641
http://dx.doi.org/10.3390/pathogens11111391
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