Assessment of Crosslinkers between Peptide Antigen and Carrier Protein for Fusion Peptide-Directed Vaccines against HIV-1

Conjugate-vaccine immunogens require three components: a carrier protein, an antigen, and a crosslinker, capable of coupling antigen to carrier protein, while preserving both T-cell responses from carrier protein and B-cell responses from antigen. We previously showed that the N-terminal eight resid...

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Detalles Bibliográficos
Autores principales: Ou, Li, Gulla, Krishana, Biju, Andrea, Biner, Daniel W., Bylund, Tatsiana, Changela, Anita, Chen, Steven J., Zheng, Cheng-Yan, Cibelli, Nicole, Corrigan, Angela R., Duan, Hongying, Gonelli, Christopher A., Kong, Wing-Pui, Cheng, Cheng, O’Dell, Sijy, Sarfo, Edward K., Shaddeau, Andrew, Wang, Shuishu, Vinitsky, Alison, Yang, Yanhong, Zhang, Baoshan, Zhang, Yaqiu, Koup, Richard A., Doria-Rose, Nicole A., Gall, Jason G., Mascola, John R., Kwong, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698951/
https://www.ncbi.nlm.nih.gov/pubmed/36423012
http://dx.doi.org/10.3390/vaccines10111916

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