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Machine-Learning Exploration of Exposure-Effect Relationships of Cisplatin in Head and Neck Cancer Patients

Background: Cisplatin is a pivotal drug in the treatment of head and neck cancer, and personalized dosage should help the preservation of an optimal toxicity–efficacy ratio. Methods: We analyzed the exposure-effect relationships of 80 adult patients with head and neck cancers and treated with standa...

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Detalles Bibliográficos
Autores principales: Cauvin, Céleste, Bourguignon, Laurent, Carriat, Laure, Mence, Abel, Ghipponi, Pauline, Salas, Sébastien, Ciccolini, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699030/
https://www.ncbi.nlm.nih.gov/pubmed/36432700
http://dx.doi.org/10.3390/pharmaceutics14112509

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