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Machine-Learning Exploration of Exposure-Effect Relationships of Cisplatin in Head and Neck Cancer Patients
Background: Cisplatin is a pivotal drug in the treatment of head and neck cancer, and personalized dosage should help the preservation of an optimal toxicity–efficacy ratio. Methods: We analyzed the exposure-effect relationships of 80 adult patients with head and neck cancers and treated with standa...
Autores principales: | Cauvin, Céleste, Bourguignon, Laurent, Carriat, Laure, Mence, Abel, Ghipponi, Pauline, Salas, Sébastien, Ciccolini, Joseph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699030/ https://www.ncbi.nlm.nih.gov/pubmed/36432700 http://dx.doi.org/10.3390/pharmaceutics14112509 |
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