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Fibroblasts secrete fibronectin under lamellipodia in a microtubule- and myosin II–dependent fashion

Fibronectin (FN) is an essential structural and regulatory component of the extracellular matrix (ECM), and its binding to integrin receptors supports cell adhesion, migration, and signaling. Here, using live-cell microscopy of fibroblasts expressing FN tagged with a pH-sensitive fluorophore, we sho...

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Detalles Bibliográficos
Autores principales: Huet-Calderwood, Clotilde, Rivera-Molina, Felix E., Toomre, Derek K., Calderwood, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699186/
https://www.ncbi.nlm.nih.gov/pubmed/36416725
http://dx.doi.org/10.1083/jcb.202204100

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