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Fibroblasts secrete fibronectin under lamellipodia in a microtubule- and myosin II–dependent fashion
Fibronectin (FN) is an essential structural and regulatory component of the extracellular matrix (ECM), and its binding to integrin receptors supports cell adhesion, migration, and signaling. Here, using live-cell microscopy of fibroblasts expressing FN tagged with a pH-sensitive fluorophore, we sho...
Autores principales: | Huet-Calderwood, Clotilde, Rivera-Molina, Felix E., Toomre, Derek K., Calderwood, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699186/ https://www.ncbi.nlm.nih.gov/pubmed/36416725 http://dx.doi.org/10.1083/jcb.202204100 |
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