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Three to Tango: Inhibitory Effect of Quercetin and Apigenin on Acetylcholinesterase, Amyloid-β Aggregation and Acetylcholinesterase-Amyloid Interaction

One of the pathological hallmarks of Alzheimer’s disease (AD) is the formation of amyloid-β plaques. Since acetylcholinesterase (AChE) promotes the formation of such plaques, the inhibition of this enzyme could slow down the progression of amyloid-β aggregation, hence being complementary to the pall...

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Detalles Bibliográficos
Autores principales: Álvarez-Berbel, Irene, Espargaró, Alba, Viayna, Antonio, Caballero, Ana Belén, Busquets, Maria Antònia, Gámez, Patrick, Luque, Francisco Javier, Sabaté, Raimon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699245/
https://www.ncbi.nlm.nih.gov/pubmed/36365159
http://dx.doi.org/10.3390/pharmaceutics14112342