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Survival and Chemosensitivity in Advanced High Grade Serous Epithelial Ovarian Cancer Patients with and without a BRCA Germline Mutation: More Evidence for Shifting the Paradigm towards Complete Surgical Cytoreduction

Background and Objectives: Approximately 10–15% of high-grade serous ovarian cancer (HGSOC) cases are related to BRCA germline mutations. Better survival rates and increased chemosensitivity are reported in patients with a BRCA 1/2 germline mutation. However, the FIGO stage and histopathological ent...

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Detalles Bibliográficos
Autores principales:	De Jong, Diederick, Otify, Mohamed, Chen, Inga, Jackson, David, Jayasinghe, Kelum, Nugent, David, Thangavelu, Amudha, Theophilou, Georgios, Laios, Alexandros
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699274/ https://www.ncbi.nlm.nih.gov/pubmed/36363568 http://dx.doi.org/10.3390/medicina58111611

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