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Structure-Based Discovery and Characterization of a Preclinical Drug Candidate for the Treatment of HIV-1 Infection

HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) area key component of the current HIV-1 combination drug regimens. Although they exhibit potent anti-HIV-1 activity and modest toxicity, the emergence of mutant strains limits their application in clinical. Our previous research efforts...

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Detalles Bibliográficos
Autores principales:	Kang, Dongwei, Yang, Jinxuan, Kong, Lingjin, Luo, Ronghua, Huang, Xusheng, Zhang, Tao, Ma, Mengdi, Feng, Da, Wang, Zhao, Fang, Hao, Zhan, Peng, Zheng, Yongtang, Liu, Xinyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699427/ https://www.ncbi.nlm.nih.gov/pubmed/36366488 http://dx.doi.org/10.3390/v14112390

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