Arteannuin-B and (3-Chlorophenyl)-2-Spiroisoxazoline Derivative Exhibit Anti-Inflammatory Effects in LPS-Activated RAW 264.7 Macrophages and BALB/c Mice-Induced Proinflammatory Responses via Downregulation of NF-κB/P38 MAPK Signaling

Host inflammatory responses are key to protection against injury; however, persistent inflammation is detrimental and contributes to morbidity and mortality. Herein, we demonstrated the anti-inflammatory role of Arteannuin-B (1) and its new spirocyclic-2-isoxazoline derivative JR-9 and their side ef...

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Detalles Bibliográficos
Autores principales: Sawhney, Gifty, Rasool, Javeed Ur, Saroch, Diksha, Ozturk, Mumin, Brombacher, Frank, Ahmad, Bilal, Bhagat, Asha, Ali, Asif, Parihar, Suraj P., Ahmed, Zabeer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699497/
https://www.ncbi.nlm.nih.gov/pubmed/36432169
http://dx.doi.org/10.3390/molecules27228068

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