Characterizing OPRM1 DNA methylation in prescription opioid users with chronic musculoskeletal pain

INTRODUCTION: Many patients with chronic pain use prescription opioids. Epigenetic modification of the μ-opioid receptor 1 (OPRM1) gene, which codes for the target protein of opioids, may influence vulnerability to opioid abuse and response to opioid pharmacotherapy, potentially affecting pain outco...

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Detalles Bibliográficos
Autores principales: Sheikh, Sophia, Smotherman, Carmen, Patel, Monika, Langaee, Taimour, Wang, Danxin, Swaray, Edward, Velasquez, Esteban, Schmidt, Siegfried O.F., Hendry, Phyllis, Cavallari, Larisa H., Fillingim, Roger B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Musculoskeletal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699511/
https://www.ncbi.nlm.nih.gov/pubmed/36447952
http://dx.doi.org/10.1097/PR9.0000000000001046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699511/
https://www.ncbi.nlm.nih.gov/pubmed/36447952
http://dx.doi.org/10.1097/PR9.0000000000001046

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