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Sex and Circadian Timing Modulate Oxaliplatin Hematological and Hematopoietic Toxicities

Oxaliplatin was nearly twice as hematotoxic, with optimal circadian timing differing by 6 h, in women as compared to men with colorectal cancers. Hence, we investigated sex- and timing-related determinants of oxaliplatin hematopoietic toxicities in mice. Body-weight loss (BWL), blood cell counts, bo...

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Detalles Bibliográficos
Autores principales:	Dulong, Sandrine, de Souza, Lucas Eduardo Botelho, Machowiak, Jean, Peuteman, Benoit, Duvallet, Gaelle, Boyenval, Déborah, Roth, Elise, Asgarova, Afag, Chang, Yunhua, Li, Xiao-Mei, Foudi, Adlen, Ballesta, Annabelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699532/ https://www.ncbi.nlm.nih.gov/pubmed/36432655 http://dx.doi.org/10.3390/pharmaceutics14112465

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