Bioadhesive Tannic-Acid-Functionalized Zein Coating Achieves Engineered Colonic Delivery of IBD Therapeutics via Reservoir Microdevices

The biggest challenge in oral delivery of anti-inflammatory drugs such as 5-aminosalicylic acid (5-ASA) is to (i) prevent rapid absorption in the small intestine and (ii) achieve localized release at the site of inflammation in the lower gut, i.e., the colon. Here, we present an advanced biopolymeri...

Descripción completa

Detalles Bibliográficos
Autores principales: Kamguyan, Khorshid, Kjeldsen, Rolf Bech, Moghaddam, Saeed Zajforoushan, Nielsen, Melanie Randahl, Thormann, Esben, Zór, Kinga, Nielsen, Line Hagner, Boisen, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699562/
https://www.ncbi.nlm.nih.gov/pubmed/36432727
http://dx.doi.org/10.3390/pharmaceutics14112536

Ejemplares similares

Ejemplares similares