Cargando…

SWATH Mass Spectrometry-Based CSF Proteome Profile of GBA-Linked Parkinson’s Disease Patients

β-glucocerebrosidase (GBA)-associated mutations are a significant risk factor for Parkinson’s disease (PD) that aggravate the disease pathology by upregulating the deposition of α-Synuclein (α-Syn). The resultant clinical profile varies for PD patients without GBA mutations. The current study aimed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zafar, Saima, Noor, Aneeqa, Younas, Neelam, Shafiq, Mohsin, Schmitz, Matthias, Wurster, Isabel, Brockmann, Kathrin, Gasser, Thomas, Zerr, Inga
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699576/ https://www.ncbi.nlm.nih.gov/pubmed/36430645 http://dx.doi.org/10.3390/ijms232214166

Ejemplares similares

Prion protein oligomers cause neuronal cytoskeletal damage in rapidly progressive Alzheimer’s disease
por: Shafiq, Mohsin, et al.
Publicado: (2021)

Molecular Profiles of Amyloid-β Proteoforms in Typical and Rapidly Progressive Alzheimer’s Disease
por: Noor, Aneeqa, et al.
Publicado: (2021)

SFPQ and Tau: critical factors contributing to rapid progression of Alzheimer’s disease
por: Younas, Neelam, et al.
Publicado: (2020)

Neurodegenerative Proteinopathies in the Proteoform Spectrum—Tools and Challenges
por: Noor, Aneeqa, et al.
Publicado: (2021)

Inflammatory CSF profiles and longitudinal development of cognitive decline in sporadic and GBA-associated PD
por: Lerche, Stefanie, et al.
Publicado: (2023)

Animal TSEs and public health: What remains of past lessons?
por: Zafar, Saima, et al.
Publicado: (2018)

Differential interactome mapping of aggregation prone/prion-like proteins under stress: novel links to stress granule biology
por: Younas, Neelam, et al.
Publicado: (2023)

Unveiling the Physical and Functional Niches of FAM26F by Analyzing Its Subcellular Localization and Novel Interacting Partners
por: Malik, Uzma, et al.
Publicado: (2020)

Proteomic profiling of soft tissue sarcomas with SWATH mass spectrometry
por: Milighetti, Martina, et al.
Publicado: (2021)

Dual-Task Performance in GBA Parkinson's Disease
por: Srulijes, Karin, et al.
Publicado: (2017)

Proteomic analysis of synovial fluid in osteoarthritis using SWATH-mass spectrometry
por: Liao, Weixiong, et al.
Publicado: (2018)

GBA-Associated Synucleinopathies: Prime Candidates for Alpha-Synuclein Targeting Compounds
por: Brockmann, Kathrin
Publicado: (2020)

Characteristic CSF Prion Seeding Efficiency in Humans with Prion Diseases
por: Cramm, Maria, et al.
Publicado: (2014)

Genetic Variants Associated with the Age of Onset Identified by Whole-Exome Sequencing in Fatal Familial Insomnia
por: Thüne, Katrin, et al.
Publicado: (2023)

α-Synuclein conformers reveal link to clinical heterogeneity of α-synucleinopathies
por: Schmitz, Matthias, et al.
Publicado: (2023)

Progress in CSF biomarker discovery in sCJD
por: Llorens, Franc, et al.
Publicado: (2016)

Identification of blood biomarkers in glioblastoma by SWATH mass spectrometry and quantitative targeted absolute proteomics
por: Miyauchi, Eisuke, et al.
Publicado: (2018)

The role of cellular prion protein in lipid metabolism in the liver
por: Arora, Amandeep Singh, et al.
Publicado: (2020)

High-throughput proteomics of nanogram-scale samples with Zeno SWATH MS
por: Wang, Ziyue, et al.
Publicado: (2022)

SWATH mass spectrometry as a tool for quantitative profiling of the matrisome
por: Krasny, Lukas, et al.
Publicado: (2018)

GBA-associated PD: chances and obstacles for targeted treatment strategies
por: Höglinger, Günter, et al.
Publicado: (2022)

Proteomics Profiling of Stool Samples from Preterm Neonates with SWATH/DIA Mass Spectrometry for Predicting Necrotizing Enterocolitis
por: Gagné, David, et al.
Publicado: (2022)

Comparison of fractionation proteomics for local SWATH library building
por: Govaert, Elisabeth, et al.
Publicado: (2017)

Complex‐centric proteome profiling by SEC‐SWATH‐MS
por: Heusel, Moritz, et al.
Publicado: (2019)

Linking the phenotype of SNCA Triplication with PET-MRI imaging pattern and alpha-synuclein CSF seeding
por: Wurster, Isabel, et al.
Publicado: (2022)

Cellular prion protein mediates early apoptotic proteome alternation and phospho-modification in human neuroblastoma cells
por: Zafar, Saima, et al.
Publicado: (2017)

Breast Cancer Classification Based on Proteotypes Obtained by SWATH Mass Spectrometry
por: Bouchal, Pavel, et al.
Publicado: (2019)

Tracking genome-editing and associated molecular perturbations by SWATH mass spectrometry
por: Lin, Qifeng, et al.
Publicado: (2019)

SWATH2stats: An R/Bioconductor Package to Process and Convert Quantitative SWATH-MS Proteomics Data for Downstream Analysis Tools
por: Blattmann, Peter, et al.
Publicado: (2016)

Tear Proteomics in Keratoconus: A Quantitative SWATH-MS Analysis
por: López-López, Maite, et al.
Publicado: (2021)

Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry
por: Collins, Ben C., et al.
Publicado: (2017)

Validation of α-Synuclein as a CSF Biomarker for Sporadic Creutzfeldt-Jakob Disease
por: Llorens, Franc, et al.
Publicado: (2017)

CSF and Serum Levels of Inflammatory Markers in PD: Sparse Correlation, Sex Differences and Association With Neurodegenerative Biomarkers
por: Lerche, Stefanie, et al.
Publicado: (2022)

SWATH-MS data of Drosophila melanogaster proteome dynamics during embryogenesis
por: Fabre, Bertrand, et al.
Publicado: (2016)

A Swath Label-Free Proteomics insight into the Faah(−/−) Mouse Liver
por: Hamid, Zeeshan, et al.
Publicado: (2018)

A mouse SWATH-mass spectrometry reference spectral library enables deconvolution of species-specific proteomic alterations in human tumour xenografts
por: Krasny, Lukas, et al.
Publicado: (2020)

Precise Temporal Profiling of Signaling Complexes in Primary Cells Using SWATH Mass Spectrometry
por: Caron, Etienne, et al.
Publicado: (2017)

Data‐independent acquisition‐based SWATH‐MS for quantitative proteomics: a tutorial
por: Ludwig, Christina, et al.
Publicado: (2018)

A Prostate Cancer Proteomics Database for SWATH-MS Based Protein Quantification
por: Muazzam, Ammara, et al.
Publicado: (2021)

Proteomic profiling of idiopathic Parkinson's disease primary patient cells by SWATH‐MS
por: Wood, Stephen A., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_49nme169h101mpj8unr2aj22q9