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Gammaherpesvirus infection drives age-associated B cells toward pathogenicity in EAE and MS

While age-associated B cells (ABCs) are known to expand and persist following viral infection and during autoimmunity, their interactions are yet to be studied together in these contexts. Here, we directly compared CD11c(+)T-bet(+) ABCs using models of Epstein-Barr virus (EBV), gammaherpesvirus 68 (...

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Detalles Bibliográficos
Autores principales: Mouat, Isobel C., Allanach, Jessica R., Fettig, Naomi M., Fan, Vina, Girard, Anna M., Shanina, Iryna, Osborne, Lisa C., Vorobeychik, Galina, Horwitz, Marc S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699667/
https://www.ncbi.nlm.nih.gov/pubmed/36427301
http://dx.doi.org/10.1126/sciadv.ade6844