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Parental mutations influence wild-type offspring via transcriptional adaptation

Transgenerational epigenetic inheritance (TEI) is mostly discussed in the context of physiological or environmental factors. Here, we show intergenerational and transgenerational inheritance of transcriptional adaptation (TA), a process whereby mutant messenger RNA (mRNA) degradation affects gene ex...

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Detalles Bibliográficos
Autores principales:	Jiang, Zhen, El-Brolosy, Mohamed A., Serobyan, Vahan, Welker, Jordan M., Retzer, Nicholas, Dooley, Christopher M., Jakutis, Gabrielius, Juan, Thomas, Fukuda, Nana, Maischein, Hans-Martin, Balciunas, Darius, Stainier, Didier Y.R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699682/ https://www.ncbi.nlm.nih.gov/pubmed/36427314 http://dx.doi.org/10.1126/sciadv.abj2029

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