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A deubiquitination module essential for T(reg) fitness in the tumor microenvironment

The tumor microenvironment (TME) enhances regulatory T (T(reg)) cell stability and immunosuppressive functions through up-regulation of lineage transcription factor Foxp3, a phenomenon known as T(reg) fitness or adaptation. Here, we characterize previously unknown TME-specific cellular and molecular...

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Detalles Bibliográficos
Autores principales:	Montauti, Elena, Weinberg, Samuel E., Chu, Peng, Chaudhuri, Shuvam, Mani, Nikita L., Iyer, Radhika, Zhou, Yuanzhang, Zhang, Yusi, Liu, Changhong, Xin, Chen, Gregory, Shana, Wei, Juncheng, Zhang, Yana, Chen, Wantao, Sun, Zhaolin, Yan, Ming, Fang, Deyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699683/ https://www.ncbi.nlm.nih.gov/pubmed/36427305 http://dx.doi.org/10.1126/sciadv.abo4116

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