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Chronic Ca(2+) imaging of cortical neurons with long-term expression of GCaMP-X
Dynamic Ca(2+) signals reflect acute changes in membrane excitability, and also mediate signaling cascades in chronic processes. In both cases, chronic Ca(2+) imaging is often desired, but challenged by the cytotoxicity intrinsic to calmodulin (CaM)-based GCaMP, a series of genetically-encoded Ca(2+...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699699/ https://www.ncbi.nlm.nih.gov/pubmed/36196992 http://dx.doi.org/10.7554/eLife.76691 |