Cargando…

Multilevel data integration and molecular docking approach to systematically elucidate the underlying pharmacological mechanisms of Er-Zhi-Wan against hepatocellular carcinoma

As a multicomponent, multitarget empirical therapy, traditional Chinese medicine (TCM) has been used clinically in Asia for thousands of years. Due to this unique feature, TCM therapy is considered a promising therapeutic strategy for the treatment of hepatocellular carcinoma (HCC). Er-Zhi-Wan (EZW)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Shaoyan, Pan, Botao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699749/ https://www.ncbi.nlm.nih.gov/pubmed/36347033 http://dx.doi.org/10.18632/aging.204369

Ejemplares similares

Exploring the mechanisms of Gui Zhi Fu Ling Wan on varicocele via network pharmacology and molecular docking
por: Wang, Ruipeng, et al.
Publicado: (2022)

Comparative In Vitro Dissolution of Two Commercially Available Er-Zhi-Wan Herbal Medicinal Products
por: Wang, M., et al.
Publicado: (2015)

System Pharmacology-Based Strategy to Decode the Synergistic Mechanism of Zhi-zhu Wan for Functional Dyspepsia
por: Wang, Chun, et al.
Publicado: (2018)

Elucidating the pharmacological mechanism by which Si-Wu-Tang induces cellular senescence in breast cancer via multilevel data integration
por: Zhao, Minhong, et al.
Publicado: (2022)

Accumulation of Arsenic Speciation and In Vivo Toxicity Following Oral Administration of a Chinese Patent Medicine Xiao-Er-Zhi-Bao-Wan in Rats
por: Luo, Jiaoyang, et al.
Publicado: (2017)

Exploring the mechanisms underlying the therapeutic effect of the Radix Bupleuri-Rhizoma Cyperi herb pair on hepatocellular carcinoma using multilevel data integration and molecular docking
por: Qing, Luzhi, et al.
Publicado: (2022)

Utilizing network pharmacology and molecular docking to explore the underlying mechanism of Guizhi Fuling Wan in treating endometriosis
por: Wang, Haoxian, et al.
Publicado: (2021)

Gyejibongnyeong-Hwan (Gui Zhi Fu Ling Wan) Ameliorates Human Uterine Myomas via Apoptosis
por: Lee, So Min, et al.
Publicado: (2019)

Hainan zhi wu zhi /
Publicado: (1964)

Yuan-Zhi decoction in the treatment of Alzheimer’s disease: An integrated approach based on chemical profiling, network pharmacology, molecular docking and experimental evaluation
por: Wu, Qiong, et al.
Publicado: (2022)

Deciphering the Potential Pharmaceutical Mechanism of GUI-ZHI-FU-LING-WAN on Systemic Sclerosis based on Systems Biology Approaches
por: Wang, Qiao, et al.
Publicado: (2019)

Integrating Network Pharmacology and Experimental Validation Deciphers the Mechanism of Guizhi Fuling Wan against Adenomyosis
por: Wang, Haoxian, et al.
Publicado: (2021)

Network Pharmacology Identifies the Mechanisms of Sang-Xing-Zhi-Ke-Fang against Pharyngitis
por: Deng, Yinhe, et al.
Publicado: (2020)

Network pharmacology prediction and molecular docking-based strategy to discover the potential pharmacological mechanism of Huang–Qi–Gui–Zhi–Wu–Wu decoction against deep vein thrombosis
por: Fan, Wei, et al.
Publicado: (2023)

Pharmacological Mechanisms Underlying the Hepatoprotective Effects of Ecliptae herba on Hepatocellular Carcinoma
por: Pan, Botao, et al.
Publicado: (2021)

Network Pharmacology and Molecular Docking to Elucidate the Potential Mechanism of Ligusticum Chuanxiong Against Osteoarthritis
por: Xiang, Cheng, et al.
Publicado: (2022)

Exploring Active Compounds and Mechanisms of Angong Niuhuang Wan on Ischemic Stroke Based on Network Pharmacology and Molecular Docking
por: Zhang, Yasu, et al.
Publicado: (2022)

Traditional Chinese decoction Si Zhi Wan attenuates ovariectomy (OVX)-induced bone loss by inhibiting osteoclastogenesis and promoting apoptosis of mature osteoclasts
por: He, Qingman, et al.
Publicado: (2022)

Integrated System Pharmacology Approaches to Elucidate Multi-Target Mechanism of Solanum surattense against Hepatocellular Carcinoma
por: Khalid, Hafiz Rameez, et al.
Publicado: (2022)

Analysis of the Mechanism of GuizhiFuling Wan in Treating Adenomyosis Based on Network Pharmacology Combined with Molecular Docking and Experimental Verification
por: Shi, Yaxin, et al.
Publicado: (2022)

Network Pharmacology and Molecular Docking Elucidate the Pharmacological Mechanism of the OSTEOWONDER Capsule for Treating Osteoporosis
por: Fan, Jiashuang, et al.
Publicado: (2022)

Integrated Network Pharmacology Analysis and Experimental Validation to Investigate the Mechanism of Zhi-Zi-Hou-Po Decoction in Depression
por: Bai, Yongtao, et al.
Publicado: (2021)

Different Influences on Tacrolimus Pharmacokinetics by Coadministrations of Zhi Ke and Zhi Shi in Rats
por: Lin, Shiuan-Pey, et al.
Publicado: (2011)

Promotion of Hair Regrowth in Androgenetic Alopecia with Supplemented Erzhi Wan: Exploring Its Mechanism Using Network Pharmacology and Molecular Docking
por: Ji, Chen, et al.
Publicado: (2023)

Keishibukuryogan (Gui-Zhi-Fu-Ling-Wan), a Kampo Formula, Decreases Disease Activity and Soluble Vascular Adhesion Molecule-1 in Patients with Rheumatoid Arthritis
por: Nozaki, Kazuya, et al.
Publicado: (2006)

Underlying Mechanisms of Bergenia spp. to Treat Hepatocellular Carcinoma Using an Integrated Network Pharmacology and Molecular Docking Approach
por: Hussain, Shoukat, et al.
Publicado: (2023)

Elucidation of the Underlying Mechanism of Gujian Oral Liquid Acting on Osteoarthritis through Network Pharmacology, Molecular Docking, and Experiment
por: Wu, Congzi, et al.
Publicado: (2022)

Identification of the Active Compound of Liu Wei Di Huang Wan for Treatment of Gestational Diabetes Mellitus via Network Pharmacology and Molecular Docking
por: Xiong, Yunqi, et al.
Publicado: (2022)

Mechanisms of dihydromyricetin against hepatocellular carcinoma elucidated by network pharmacology combined with experimental validation
por: Zhang, Shuo, et al.
Publicado: (2023)

Network Pharmacology and Molecular Docking Elucidate the Underlying Pharmacological Mechanisms of the Herb Houttuynia cordata in Treating Pneumonia Caused by SARS-CoV-2
por: Liu, Junying, et al.
Publicado: (2022)

Network pharmacology and molecular docking elucidate potential mechanisms of Eucommia ulmoides in hepatic ischemia–reperfusion injury
por: Ma, Xuan, et al.
Publicado: (2023)

Application of network pharmacology and molecular docking to elucidate the potential mechanism of Eucommia ulmoides-Radix Achyranthis Bidentatae against osteoarthritis
por: Jian, Gong-hui, et al.
Publicado: (2020)

Elucidation of Agonist and Antagonist Dynamic Binding Patterns in ER-α by Integration of Molecular Docking, Molecular Dynamics Simulations and Quantum Mechanical Calculations
por: Sakkiah, Sugunadevi, et al.
Publicado: (2021)

Elucidation of Danzhixiaoyao Wan and Its Constituent Herbs on Antioxidant Activity and Inhibition of Nitric Oxide Production
por: Liao, Hui, et al.
Publicado: (2007)

Integrated Screening of Effective Anti-Insomnia Fractions of Zhi-Zi-Hou-Po Decoction via Drosophila melanogaster and Network Pharmacology Analysis of the Underlying Pharmacodynamic Material and Mechanism
por: Sun, Yu, et al.
Publicado: (2021)

Network pharmacology and molecular docking to elucidate the mechanism of pulsatilla decoction in the treatment of colon cancer
por: Liu, Huan, et al.
Publicado: (2022)

Anti-Autophagy Mechanism of Zhi Gan Prescription Based on Network Pharmacology in Nonalcoholic Steatohepatitis Rats
por: Qin, Chufeng, et al.
Publicado: (2021)

A network pharmacology approach to investigate the pharmacological effects of Guizhi Fuling Wan on uterine fibroids
por: Zeng, Liuting, et al.
Publicado: (2017)

Network Pharmacology Study to Elucidate the Key Targets of Underlying Antihistamines against COVID-19
por: Oh, Ki-Kwang, et al.
Publicado: (2022)

The effectiveness of a modified Gui Zhi Fu Ling Wan formulation (Gynoclear™) for the treatment of endometriosis: a study protocol for a placebo-controlled, double-blind, randomised controlled trial
por: Armour, Mike, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_a435cuh3rhejo09ht6n0p2b4o4