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Intracranial aneurysms in pediatric population treated with flow diverters: A single-center experience

BACKGROUND: Pediatric intracranial aneurysms (PIAs) are uncommon. Flow diverters (FDs) have shown to be effective on treatment of selected aneurysms. METHODS: We describe 10 cases of PIAs treated with FDs at one medical center in Mexico, from April 2015 to April 2020. RESULTS: Out of 230 patients tr...

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Autores principales: Santos-Franco, Jorge Arturo, Cruz-Argüelles, Carlos Antonio, Agustin-Aguilar, Fernando, Abrego-Salinas, Adrián Alejandro, Casas-Martínez, Martín Roberto, Olivares-Peña, Jorge Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific Scholar 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699858/
https://www.ncbi.nlm.nih.gov/pubmed/36447852
http://dx.doi.org/10.25259/SNI_873_2022
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author Santos-Franco, Jorge Arturo
Cruz-Argüelles, Carlos Antonio
Agustin-Aguilar, Fernando
Abrego-Salinas, Adrián Alejandro
Casas-Martínez, Martín Roberto
Olivares-Peña, Jorge Luis
author_facet Santos-Franco, Jorge Arturo
Cruz-Argüelles, Carlos Antonio
Agustin-Aguilar, Fernando
Abrego-Salinas, Adrián Alejandro
Casas-Martínez, Martín Roberto
Olivares-Peña, Jorge Luis
author_sort Santos-Franco, Jorge Arturo
collection PubMed
description BACKGROUND: Pediatric intracranial aneurysms (PIAs) are uncommon. Flow diverters (FDs) have shown to be effective on treatment of selected aneurysms. METHODS: We describe 10 cases of PIAs treated with FDs at one medical center in Mexico, from April 2015 to April 2020. RESULTS: Out of 230 patients treated with FDs, 10 (4.3%) were pediatric. Average age was 9.4 years old (R: 6–15). Two patients (20%) had subarachnoid hemorrhage, 3 had epilepsy (30%), 3 (30%) had clinical signs of cranial nerve compression, and 4 (40%) had only headache. Two patients were in 1a grade of Hunt and Kosnik scale. Out of the nonruptured aneurysms, 7 (70%) were in 15 points of Glasgow Coma Scale and 1 patient (10%) was in 13 points. Treatment was performed without complications; nevertheless, appropriate distal deployment was not achieved in one case. At discharge, nine patients had 5 points of Glasgow Outcome Scale. All patients underwent computed tomography angiography or digital subtraction angiography at 1, 3, 6, and 12 months, 2 patients (20%) had a 2-year follow-up, and 3 patients (30%) had a 3-year follow-up. According to Kamran grading scale, 9 patients (90%) were classified as Grade 4 and 1 patient (10%) as Grade 3. CONCLUSION: Even though it is a small series, as this is an uncommon disease, we may suggest that FDs are useful to treat properly selected PIAs. Our study has consecutive imaging assessment at least a year of follow-up in which aneurysm stable occlusion was observed in 90% of patients.
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spelling pubmed-96998582022-11-28 Intracranial aneurysms in pediatric population treated with flow diverters: A single-center experience Santos-Franco, Jorge Arturo Cruz-Argüelles, Carlos Antonio Agustin-Aguilar, Fernando Abrego-Salinas, Adrián Alejandro Casas-Martínez, Martín Roberto Olivares-Peña, Jorge Luis Surg Neurol Int Original Article BACKGROUND: Pediatric intracranial aneurysms (PIAs) are uncommon. Flow diverters (FDs) have shown to be effective on treatment of selected aneurysms. METHODS: We describe 10 cases of PIAs treated with FDs at one medical center in Mexico, from April 2015 to April 2020. RESULTS: Out of 230 patients treated with FDs, 10 (4.3%) were pediatric. Average age was 9.4 years old (R: 6–15). Two patients (20%) had subarachnoid hemorrhage, 3 had epilepsy (30%), 3 (30%) had clinical signs of cranial nerve compression, and 4 (40%) had only headache. Two patients were in 1a grade of Hunt and Kosnik scale. Out of the nonruptured aneurysms, 7 (70%) were in 15 points of Glasgow Coma Scale and 1 patient (10%) was in 13 points. Treatment was performed without complications; nevertheless, appropriate distal deployment was not achieved in one case. At discharge, nine patients had 5 points of Glasgow Outcome Scale. All patients underwent computed tomography angiography or digital subtraction angiography at 1, 3, 6, and 12 months, 2 patients (20%) had a 2-year follow-up, and 3 patients (30%) had a 3-year follow-up. According to Kamran grading scale, 9 patients (90%) were classified as Grade 4 and 1 patient (10%) as Grade 3. CONCLUSION: Even though it is a small series, as this is an uncommon disease, we may suggest that FDs are useful to treat properly selected PIAs. Our study has consecutive imaging assessment at least a year of follow-up in which aneurysm stable occlusion was observed in 90% of patients. Scientific Scholar 2022-11-11 /pmc/articles/PMC9699858/ /pubmed/36447852 http://dx.doi.org/10.25259/SNI_873_2022 Text en Copyright: © 2022 Surgical Neurology International https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, transform, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Santos-Franco, Jorge Arturo
Cruz-Argüelles, Carlos Antonio
Agustin-Aguilar, Fernando
Abrego-Salinas, Adrián Alejandro
Casas-Martínez, Martín Roberto
Olivares-Peña, Jorge Luis
Intracranial aneurysms in pediatric population treated with flow diverters: A single-center experience
title Intracranial aneurysms in pediatric population treated with flow diverters: A single-center experience
title_full Intracranial aneurysms in pediatric population treated with flow diverters: A single-center experience
title_fullStr Intracranial aneurysms in pediatric population treated with flow diverters: A single-center experience
title_full_unstemmed Intracranial aneurysms in pediatric population treated with flow diverters: A single-center experience
title_short Intracranial aneurysms in pediatric population treated with flow diverters: A single-center experience
title_sort intracranial aneurysms in pediatric population treated with flow diverters: a single-center experience
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699858/
https://www.ncbi.nlm.nih.gov/pubmed/36447852
http://dx.doi.org/10.25259/SNI_873_2022
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