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Lumbar epidural blood patch: An effective treatment for intracranial hypotension

BACKGROUND: The literature has demonstrated the efficacy of lumbar epidural blood patch (LEBP) in the management of spontaneous intracranial hypotension (SIH). However, the underlying pathophysiology of such management remains unclear. In this study, we aim to evaluate the utility of LEBP injections...

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Autores principales: Leung, Lok Wa Laura, Chan, Yuen Chung David, Chan, Tat Ming Danny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific Scholar 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699889/
https://www.ncbi.nlm.nih.gov/pubmed/36447895
http://dx.doi.org/10.25259/SNI_795_2022
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author Leung, Lok Wa Laura
Chan, Yuen Chung David
Chan, Tat Ming Danny
author_facet Leung, Lok Wa Laura
Chan, Yuen Chung David
Chan, Tat Ming Danny
author_sort Leung, Lok Wa Laura
collection PubMed
description BACKGROUND: The literature has demonstrated the efficacy of lumbar epidural blood patch (LEBP) in the management of spontaneous intracranial hypotension (SIH). However, the underlying pathophysiology of such management remains unclear. In this study, we aim to evaluate the utility of LEBP injections in the management of SIH and develop a potential management algorithm used in the triage and management of SIH patients. METHODS: We retrospectively examined the clinical case notes of 14 patients with SIH (age: 25–69 years) who were managed with LEBP injections during the year of 2016–2021. We evaluated the presenting symptoms of each selected patient and radiological findings as well as treatment outcomes. Our aim is to evaluate the effectiveness of LEBP in the treatment of SIH patients through follow-up clinical and imaging assessment. RESULTS: About 93% of patients describe the presence of headache at presentation, while 43% describe it as being of an orthostatic nature. All patients demonstrated typical findings on magnetic resonance imaging brain. Treatment success assessed through symptomatic improvement and radiological resolution was found in 85% of our patients at a 2-month interval. CONCLUSION: LEBP injection is an effective method of management in patients with a diagnosis of SIH. It should be considered in all SIH patients irrespective of whether a “dural leak” can be localized through radiological investigations.
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spelling pubmed-96998892022-11-28 Lumbar epidural blood patch: An effective treatment for intracranial hypotension Leung, Lok Wa Laura Chan, Yuen Chung David Chan, Tat Ming Danny Surg Neurol Int Original Article BACKGROUND: The literature has demonstrated the efficacy of lumbar epidural blood patch (LEBP) in the management of spontaneous intracranial hypotension (SIH). However, the underlying pathophysiology of such management remains unclear. In this study, we aim to evaluate the utility of LEBP injections in the management of SIH and develop a potential management algorithm used in the triage and management of SIH patients. METHODS: We retrospectively examined the clinical case notes of 14 patients with SIH (age: 25–69 years) who were managed with LEBP injections during the year of 2016–2021. We evaluated the presenting symptoms of each selected patient and radiological findings as well as treatment outcomes. Our aim is to evaluate the effectiveness of LEBP in the treatment of SIH patients through follow-up clinical and imaging assessment. RESULTS: About 93% of patients describe the presence of headache at presentation, while 43% describe it as being of an orthostatic nature. All patients demonstrated typical findings on magnetic resonance imaging brain. Treatment success assessed through symptomatic improvement and radiological resolution was found in 85% of our patients at a 2-month interval. CONCLUSION: LEBP injection is an effective method of management in patients with a diagnosis of SIH. It should be considered in all SIH patients irrespective of whether a “dural leak” can be localized through radiological investigations. Scientific Scholar 2022-11-11 /pmc/articles/PMC9699889/ /pubmed/36447895 http://dx.doi.org/10.25259/SNI_795_2022 Text en Copyright: © 2022 Surgical Neurology International https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, transform, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Leung, Lok Wa Laura
Chan, Yuen Chung David
Chan, Tat Ming Danny
Lumbar epidural blood patch: An effective treatment for intracranial hypotension
title Lumbar epidural blood patch: An effective treatment for intracranial hypotension
title_full Lumbar epidural blood patch: An effective treatment for intracranial hypotension
title_fullStr Lumbar epidural blood patch: An effective treatment for intracranial hypotension
title_full_unstemmed Lumbar epidural blood patch: An effective treatment for intracranial hypotension
title_short Lumbar epidural blood patch: An effective treatment for intracranial hypotension
title_sort lumbar epidural blood patch: an effective treatment for intracranial hypotension
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699889/
https://www.ncbi.nlm.nih.gov/pubmed/36447895
http://dx.doi.org/10.25259/SNI_795_2022
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