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Modelling acute antibody-mediated rejection of human kidney transplants using ex-vivo warm machine perfusion

BACKGROUND: Transplant rejection is a major cause of graft loss and morbidity. Currently, no human models of antibody-mediated rejection (AMR) exist, limiting mechanistic investigation and organ-specific targeted therapy. Here, using 12 human kidneys and ex-vivo normothermic machine perfusion, we de...

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Detalles Bibliográficos
Autores principales:	Chandak, Pankaj, Phillips, Benedict L., Bennett, Danothy, Uwechue, Raphael, Kessaris, Nicos, Shaw, Olivia, Maggs, Tim, Woodford, Luke, Veniard, David, Perera, Ranmith, Parmar, Kiran, Hunt, Beverley J., Callaghan, Chris, Dorling, Anthony, Mamode, Nizam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699940/ https://www.ncbi.nlm.nih.gov/pubmed/36427468 http://dx.doi.org/10.1016/j.ebiom.2022.104365

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