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OR04-2 WNT2B Deficiency Results in Hyperreninemic Hypoaldosteronism in Humans and Mice

Proper development and zonation of the adrenal cortex is intimately connected with its lifelong capacity to produce steroid hormones. Both adrenocortical development and homeostasis are mediated in part by paracrine WNT/β-catenin signaling, an essential pathway for zonal maintenance and aldosterone...

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Detalles Bibliográficos
Autores principales: Azova, Svetlana, Basham, Kaitlin, Breault, David, Hammer, Gary, LaPensee, Christopher, O’Connell, Amy, Ribeiro, Claudio, Silva Borges, Kleiton, Turcu, Adina, Little III, Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700277/
http://dx.doi.org/10.1210/jendso/bvac150.166