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OR04-2 WNT2B Deficiency Results in Hyperreninemic Hypoaldosteronism in Humans and Mice
Proper development and zonation of the adrenal cortex is intimately connected with its lifelong capacity to produce steroid hormones. Both adrenocortical development and homeostasis are mediated in part by paracrine WNT/β-catenin signaling, an essential pathway for zonal maintenance and aldosterone...
Autores principales: | Azova, Svetlana, Basham, Kaitlin, Breault, David, Hammer, Gary, LaPensee, Christopher, O’Connell, Amy, Ribeiro, Claudio, Silva Borges, Kleiton, Turcu, Adina, Little III, Donald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700277/ http://dx.doi.org/10.1210/jendso/bvac150.166 |
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