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Identification of Broadly Applicable Adeno-Associated Virus Vectors by Systematic Comparison of Commonly Used Capsid Variants In Vitro

Adeno-associated viruses (AAVs) represent highly attractive gene therapy vectors and potent research tools for the modulation of gene expression in animal models or difficult-to-transfect cell cultures. Engineered variants, comprising chimeric, mutated, or peptide-inserted capsids, have strongly bro...

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Detalles Bibliográficos
Autores principales: Weinmann, Jonas, Söllner, Julia, Abele, Sarah, Zimmermann, Gudrun, Zuckschwerdt, Kai, Mayer, Christine, Danner-Liskus, Jenny, Peltzer, Alexander, Schuler, Michael, Lamla, Thorsten, Strobel, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700356/
https://www.ncbi.nlm.nih.gov/pubmed/36097758
http://dx.doi.org/10.1089/hum.2022.109