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Forelimb Resistance Exercise Protects Against Neuromuscular Junction Denervation in the SOD1-G93A Rat Model of ALS

INTRODUCTION: The symptoms of Amyotrophic Lateral Sclerosis (ALS) include muscle weakness and eventual paralysis. These symptoms result from denervation of the neuromuscular junction (NMJ) and motor neuron cell death in the brain and spinal cord. Due to the “dying back” pattern of motor neuron degen...

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Detalles Bibliográficos
Autores principales: Nishimune, Hiroshi, Stanford, Kimberly G, Chen, Jie, Odum, James D, Rorie, Alexander D, Rogers, Robert S, Wheatley, Joshua L, Geiger, Paige C, Stanford, John A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700444/
https://www.ncbi.nlm.nih.gov/pubmed/36444378
http://dx.doi.org/10.2147/DNND.S388455