ATM phosphorylates PP2A subunit A resulting in nuclear export and spatiotemporal regulation of the DNA damage response

Ataxia telangiectasia mutated (ATM) is a serine–threonine protein kinase and important regulator of the DNA damage response (DDR). One critical ATM target is the structural subunit A (PR65–S401) of protein phosphatase 2A (PP2A), known to regulate diverse cellular processes such as mitosis and cell g...

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Detalles Bibliográficos
Autores principales: Sule, Amrita, Golding, Sarah E., Ahmad, Syed F., Watson, James, Ahmed, Mostafa H., Kellogg, Glen E., Bernas, Tytus, Koebley, Sean, Reed, Jason C., Povirk, Lawrence F., Valerie, Kristoffer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700600/
https://www.ncbi.nlm.nih.gov/pubmed/36434396
http://dx.doi.org/10.1007/s00018-022-04550-5

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