Cargando…

Do heritable immune responses extend physiological individuality?

Immunology and its philosophy are a primary source for thinking about biological individuality. Through its discriminatory function, the immune system is believed to delineate organism and environment within one generation, thus defining the physiological individual. Based on the paradigmatic instan...

Descripción completa

Detalles Bibliográficos
Autor principal: Juliane Veigl, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700645/
https://www.ncbi.nlm.nih.gov/pubmed/36427106
http://dx.doi.org/10.1007/s40656-022-00549-0
_version_ 1784839356980133888
author Juliane Veigl, Sophie
author_facet Juliane Veigl, Sophie
author_sort Juliane Veigl, Sophie
collection PubMed
description Immunology and its philosophy are a primary source for thinking about biological individuality. Through its discriminatory function, the immune system is believed to delineate organism and environment within one generation, thus defining the physiological individual. Based on the paradigmatic instantiations of immune systems, immune interactions and, thus, the physiological individual are believed to last only for one generation. However, in recent years, transgenerationally persisting immune responses have been reported in several phyla, but the consequences for physiological individuality have not yet been explored. In this article, I will introduce an invertebrate immune system that is RNA-based and operates through a heritable silencing/licensing paradigm. I will discuss how such a perspective on immune systems can illuminate our conceptions of individuality. I will particularly introduce an account of immunological individuality that is not restricted to one generation.
format Online
Article
Text
id pubmed-9700645
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Springer International Publishing
record_format MEDLINE/PubMed
spelling pubmed-97006452022-11-27 Do heritable immune responses extend physiological individuality? Juliane Veigl, Sophie Hist Philos Life Sci Original Paper Immunology and its philosophy are a primary source for thinking about biological individuality. Through its discriminatory function, the immune system is believed to delineate organism and environment within one generation, thus defining the physiological individual. Based on the paradigmatic instantiations of immune systems, immune interactions and, thus, the physiological individual are believed to last only for one generation. However, in recent years, transgenerationally persisting immune responses have been reported in several phyla, but the consequences for physiological individuality have not yet been explored. In this article, I will introduce an invertebrate immune system that is RNA-based and operates through a heritable silencing/licensing paradigm. I will discuss how such a perspective on immune systems can illuminate our conceptions of individuality. I will particularly introduce an account of immunological individuality that is not restricted to one generation. Springer International Publishing 2022-11-24 2022 /pmc/articles/PMC9700645/ /pubmed/36427106 http://dx.doi.org/10.1007/s40656-022-00549-0 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Paper
Juliane Veigl, Sophie
Do heritable immune responses extend physiological individuality?
title Do heritable immune responses extend physiological individuality?
title_full Do heritable immune responses extend physiological individuality?
title_fullStr Do heritable immune responses extend physiological individuality?
title_full_unstemmed Do heritable immune responses extend physiological individuality?
title_short Do heritable immune responses extend physiological individuality?
title_sort do heritable immune responses extend physiological individuality?
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700645/
https://www.ncbi.nlm.nih.gov/pubmed/36427106
http://dx.doi.org/10.1007/s40656-022-00549-0
work_keys_str_mv AT julianeveiglsophie doheritableimmuneresponsesextendphysiologicalindividuality