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Do heritable immune responses extend physiological individuality?
Immunology and its philosophy are a primary source for thinking about biological individuality. Through its discriminatory function, the immune system is believed to delineate organism and environment within one generation, thus defining the physiological individual. Based on the paradigmatic instan...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer International Publishing
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700645/ https://www.ncbi.nlm.nih.gov/pubmed/36427106 http://dx.doi.org/10.1007/s40656-022-00549-0 |
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author | Juliane Veigl, Sophie |
author_facet | Juliane Veigl, Sophie |
author_sort | Juliane Veigl, Sophie |
collection | PubMed |
description | Immunology and its philosophy are a primary source for thinking about biological individuality. Through its discriminatory function, the immune system is believed to delineate organism and environment within one generation, thus defining the physiological individual. Based on the paradigmatic instantiations of immune systems, immune interactions and, thus, the physiological individual are believed to last only for one generation. However, in recent years, transgenerationally persisting immune responses have been reported in several phyla, but the consequences for physiological individuality have not yet been explored. In this article, I will introduce an invertebrate immune system that is RNA-based and operates through a heritable silencing/licensing paradigm. I will discuss how such a perspective on immune systems can illuminate our conceptions of individuality. I will particularly introduce an account of immunological individuality that is not restricted to one generation. |
format | Online Article Text |
id | pubmed-9700645 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-97006452022-11-27 Do heritable immune responses extend physiological individuality? Juliane Veigl, Sophie Hist Philos Life Sci Original Paper Immunology and its philosophy are a primary source for thinking about biological individuality. Through its discriminatory function, the immune system is believed to delineate organism and environment within one generation, thus defining the physiological individual. Based on the paradigmatic instantiations of immune systems, immune interactions and, thus, the physiological individual are believed to last only for one generation. However, in recent years, transgenerationally persisting immune responses have been reported in several phyla, but the consequences for physiological individuality have not yet been explored. In this article, I will introduce an invertebrate immune system that is RNA-based and operates through a heritable silencing/licensing paradigm. I will discuss how such a perspective on immune systems can illuminate our conceptions of individuality. I will particularly introduce an account of immunological individuality that is not restricted to one generation. Springer International Publishing 2022-11-24 2022 /pmc/articles/PMC9700645/ /pubmed/36427106 http://dx.doi.org/10.1007/s40656-022-00549-0 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Paper Juliane Veigl, Sophie Do heritable immune responses extend physiological individuality? |
title | Do heritable immune responses extend physiological individuality? |
title_full | Do heritable immune responses extend physiological individuality? |
title_fullStr | Do heritable immune responses extend physiological individuality? |
title_full_unstemmed | Do heritable immune responses extend physiological individuality? |
title_short | Do heritable immune responses extend physiological individuality? |
title_sort | do heritable immune responses extend physiological individuality? |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700645/ https://www.ncbi.nlm.nih.gov/pubmed/36427106 http://dx.doi.org/10.1007/s40656-022-00549-0 |
work_keys_str_mv | AT julianeveiglsophie doheritableimmuneresponsesextendphysiologicalindividuality |