Escin suppresses immune cell infiltration and selectively modulates Nrf2/HO-1, TNF-α/JNK, and IL-22/STAT3 signaling pathways in concanavalin A-induced autoimmune hepatitis in mice

The current study aims to investigate the possible protective effect of escin, the active constituent of a natural mixture of triterpene saponin glycoside, against immune-mediated hepatitis driven by concanavalin A (Con A) and to elucidate its possible underlying mechanisms. Adult male mice were adm...

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Detalles Bibliográficos
Autores principales: Elshal, Mahmoud, Hazem, Sara H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700661/
https://www.ncbi.nlm.nih.gov/pubmed/36063304
http://dx.doi.org/10.1007/s10787-022-01058-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700661/
https://www.ncbi.nlm.nih.gov/pubmed/36063304
http://dx.doi.org/10.1007/s10787-022-01058-z

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