Cargando…

Tobacco use and risk of COVID-19 infection in the Finnish general population

Empirical evidence, primarily based on hospital-based or voluntary samples, suggests that current smokers have a lower risk of COVID-19 infection than never smokers. In this study, we used nationally representative data to examine the association between tobacco use and the risk of having a confirme...

Descripción completa

Detalles Bibliográficos
Autores principales: Peña, Sebastián, Ilmarinen, Katja, Kestilä, Laura, Parikka, Suvi, Kärkkäinen, Sanna, Caspersen, Ida Henriette, Shaaban, Ahmed Nabil, Magnus, Per, Galanti, Maria Rosaria, Karvonen, Sakari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700668/
https://www.ncbi.nlm.nih.gov/pubmed/36434073
http://dx.doi.org/10.1038/s41598-022-24148-y
_version_ 1784839362685435904
author Peña, Sebastián
Ilmarinen, Katja
Kestilä, Laura
Parikka, Suvi
Kärkkäinen, Sanna
Caspersen, Ida Henriette
Shaaban, Ahmed Nabil
Magnus, Per
Galanti, Maria Rosaria
Karvonen, Sakari
author_facet Peña, Sebastián
Ilmarinen, Katja
Kestilä, Laura
Parikka, Suvi
Kärkkäinen, Sanna
Caspersen, Ida Henriette
Shaaban, Ahmed Nabil
Magnus, Per
Galanti, Maria Rosaria
Karvonen, Sakari
author_sort Peña, Sebastián
collection PubMed
description Empirical evidence, primarily based on hospital-based or voluntary samples, suggests that current smokers have a lower risk of COVID-19 infection than never smokers. In this study, we used nationally representative data to examine the association between tobacco use and the risk of having a confirmed COVID-19 case. We explored several forms of tobacco use, contributing to separate the role of nicotine from smoking. We used data from 44,199 participants from three pooled national health surveys in Finland (FinSote 2018–2020). The primary outcome was a confirmed COVID-19 case. We examined current smoking, moist smokeless tobacco (snus), e-cigarettes with and without nicotine and nicotine replacement therapy products. Current daily smokers had a relative risk of 1.12 of a confirmed COVID-19 case (95% CI 0.65; 1.94) in fully adjusted models compared with never smokers. Current snus use was associated with a 68% higher risk of a confirmed COVID-19 case (RR 1.68, 95% CI 1.02; 2.75) than never users. We did not find conclusive evidence of associations between e-cigarettes with and without nicotine and nicotine replacement therapy products and the risk of confirmed COVID-19 cases. Our findings suggest that nicotine might not have a protective role in the risk of COVID-19 as previously hypothesized.
format Online
Article
Text
id pubmed-9700668
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-97006682022-11-27 Tobacco use and risk of COVID-19 infection in the Finnish general population Peña, Sebastián Ilmarinen, Katja Kestilä, Laura Parikka, Suvi Kärkkäinen, Sanna Caspersen, Ida Henriette Shaaban, Ahmed Nabil Magnus, Per Galanti, Maria Rosaria Karvonen, Sakari Sci Rep Article Empirical evidence, primarily based on hospital-based or voluntary samples, suggests that current smokers have a lower risk of COVID-19 infection than never smokers. In this study, we used nationally representative data to examine the association between tobacco use and the risk of having a confirmed COVID-19 case. We explored several forms of tobacco use, contributing to separate the role of nicotine from smoking. We used data from 44,199 participants from three pooled national health surveys in Finland (FinSote 2018–2020). The primary outcome was a confirmed COVID-19 case. We examined current smoking, moist smokeless tobacco (snus), e-cigarettes with and without nicotine and nicotine replacement therapy products. Current daily smokers had a relative risk of 1.12 of a confirmed COVID-19 case (95% CI 0.65; 1.94) in fully adjusted models compared with never smokers. Current snus use was associated with a 68% higher risk of a confirmed COVID-19 case (RR 1.68, 95% CI 1.02; 2.75) than never users. We did not find conclusive evidence of associations between e-cigarettes with and without nicotine and nicotine replacement therapy products and the risk of confirmed COVID-19 cases. Our findings suggest that nicotine might not have a protective role in the risk of COVID-19 as previously hypothesized. Nature Publishing Group UK 2022-11-25 /pmc/articles/PMC9700668/ /pubmed/36434073 http://dx.doi.org/10.1038/s41598-022-24148-y Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Peña, Sebastián
Ilmarinen, Katja
Kestilä, Laura
Parikka, Suvi
Kärkkäinen, Sanna
Caspersen, Ida Henriette
Shaaban, Ahmed Nabil
Magnus, Per
Galanti, Maria Rosaria
Karvonen, Sakari
Tobacco use and risk of COVID-19 infection in the Finnish general population
title Tobacco use and risk of COVID-19 infection in the Finnish general population
title_full Tobacco use and risk of COVID-19 infection in the Finnish general population
title_fullStr Tobacco use and risk of COVID-19 infection in the Finnish general population
title_full_unstemmed Tobacco use and risk of COVID-19 infection in the Finnish general population
title_short Tobacco use and risk of COVID-19 infection in the Finnish general population
title_sort tobacco use and risk of covid-19 infection in the finnish general population
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700668/
https://www.ncbi.nlm.nih.gov/pubmed/36434073
http://dx.doi.org/10.1038/s41598-022-24148-y
work_keys_str_mv AT penasebastian tobaccouseandriskofcovid19infectioninthefinnishgeneralpopulation
AT ilmarinenkatja tobaccouseandriskofcovid19infectioninthefinnishgeneralpopulation
AT kestilalaura tobaccouseandriskofcovid19infectioninthefinnishgeneralpopulation
AT parikkasuvi tobaccouseandriskofcovid19infectioninthefinnishgeneralpopulation
AT karkkainensanna tobaccouseandriskofcovid19infectioninthefinnishgeneralpopulation
AT caspersenidahenriette tobaccouseandriskofcovid19infectioninthefinnishgeneralpopulation
AT shaabanahmednabil tobaccouseandriskofcovid19infectioninthefinnishgeneralpopulation
AT magnusper tobaccouseandriskofcovid19infectioninthefinnishgeneralpopulation
AT galantimariarosaria tobaccouseandriskofcovid19infectioninthefinnishgeneralpopulation
AT karvonensakari tobaccouseandriskofcovid19infectioninthefinnishgeneralpopulation