Fine-mapping the immunodominant antibody epitopes on consensus sequence-based HIV-1 envelope trimer vaccine candidates

The HIV-1 envelope glycoprotein (Env) trimer is the key target for vaccines aimed at inducing neutralizing antibodies (NAbs) against HIV-1. The clinical candidate immunogen ConM SOSIP.v7 is a stabilized native-like HIV-1 Env trimer based on an artificial consensus sequence of all HIV-1 isolates in g...

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Detalles Bibliográficos
Autores principales: Reiss, E. I. M. M., van Haaren, M. M., van Schooten, J., Claireaux, M. A. F., Maisonnasse, P., Antanasijevic, A., Allen, J. D., Bontjer, I., Torres, J. L., Lee, W-H, Ozorowski, G., Vázquez Bernat, N., Kaduk, M., Aldon, Y., Burger, J. A., Chawla, H., Aartse, A., Tolazzi, M., Gao, H., Mundsperger, P., Crispin, M., Montefiori, D. C., Karlsson Hedestam, G. B., Scarlatti, G., Ward, A. B., Le Grand, R., Shattock, R., Dereuddre-Bosquet, N., Sanders, R. W., van Gils, M. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700725/
https://www.ncbi.nlm.nih.gov/pubmed/36433972
http://dx.doi.org/10.1038/s41541-022-00576-9

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